Drawing on ecological theory, the current study examined the associations of religious versus secular environments, relationship with the mother, and personal characteristics (religious coping strategies; self-mastery; sexual self-concept) with the life satisfaction of Israeli Young Modern Orthodox women and a comparison group of secular women. A sample of 362 women aged 18–29 completed quantitative questionnaires. High levels of sexual self-concept and self-mastery, positive religious coping strategies, and supportive relationship with the mother were associated with higher life satisfaction. Supportive relationships with mothers moderated the association between religious coping strategies and life satisfaction. Theoretical and practical implications are discussed.