This study deals with designing a decentralized multi-input multi-output controller board based on a low-cost microcontroller, which drives both parts of variable-speed scroll compressor and electronic-type expansion valve simultaneously in a chiller system. This study aims to show the applicability of commercial low-cost microcontroller to increase the efficiency of the chiller system, having variable-speed scroll compressor and electronic-type expansion valve with a new electronic card. Moreover, the refrigerant system proposed in this study provides the compactness, mobility, and flexibility, and also a decrease in the controller unit’s budget. The study was tested on a chiller system that consists of an air-cooled condenser, a variable-speed scroll compressor, and a stepper driven electronic-type expansion valve. The R134a was used as a refrigerant fluid and its flow was controlled by electronic-type expansion valve in this setup. Both variable-speed scroll compressor and electronic-type expansion valve were driven by the proposed hardware using either proportional integral derivative or fuzzy logic controller, which defines four distinct controller modes. The experimental results show that fuzzy logic controlled electronic-type expansion valve and proportional integral derivative controlled variable-speed scroll compressor mode give more robustness by considering the response time.