2022
DOI: 10.1080/0886022x.2022.2056053
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Development and internal validation of machine learning algorithms for end-stage renal disease risk prediction model of people with type 2 diabetes mellitus and diabetic kidney disease

Abstract: Aims Diabetic kidney disease (DKD) is the most common cause of end-stage renal disease (ESRD) and is associated with increased morbidity and mortality in patients with diabetes. Identification of risk factors involved in the progression of DKD to ESRD is expected to result in early detection and appropriate intervention and improve prognosis. Therefore, this study aimed to establish a risk prediction model for ESRD resulting from DKD in patients with type 2 diabetes mellitus (T2DM). … Show more

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Cited by 57 publications
(41 citation statements)
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“…The precise pathophysiological mechanisms behind the link between sleep traits and ESRD remain poorly known. In this and previous research, sleep characteristics were connected to obesity, hypertension, and diabetes, and ESRD may be triggered by obesity [40], high blood pressure[38], and diabetes [39,41].…”
Section: Potential Mechanismsmentioning
confidence: 51%
“…The precise pathophysiological mechanisms behind the link between sleep traits and ESRD remain poorly known. In this and previous research, sleep characteristics were connected to obesity, hypertension, and diabetes, and ESRD may be triggered by obesity [40], high blood pressure[38], and diabetes [39,41].…”
Section: Potential Mechanismsmentioning
confidence: 51%
“…In a previous study [ 31 ], a machine learning algorithm was used to develop and validate a predictive model for the risk of ESKD in patients with diabetic nephropathy, with a random forest algorithm identifying five major factors: cystatin-C, serum albumin, hemoglobin, 24-h urine urinary total protein, and eGFR (AUC 0.90 and ACC 82.65%). Zhao et al.…”
Section: Discussionmentioning
confidence: 99%
“…A dramatic rise in the prevalence of diabetes has escalated the number of CKD patients, with CKD now affecting 9.1% of the world's population (Collaboration GCKD, 2020 ). Despite therapeutic strategies to manage diabetes a significant portion of diabetic patients still end up with kidney failure (Costacou & Orchard, 2018 ; Zou et al, 2022 ).…”
Section: Introductionmentioning
confidence: 99%