Infertility is one of the major health problems of our time. In fact, infertility is caused by many factors. Among these factors the effect of vitamin D levels of infertility are overlooked. The prevalence of vitamin D deficiency varies between 20% and 66.8% in different countries. In fact, vitamin D deficiency can lead to infertility both women and man. Lack of vitamin D in women with polycystic ovary syndrome in the study, uterine fibroids, as well as has been demonstrated over a relationship with a decrease in reserves. In males it has been suggested to affect sperm count and morphology. At the same time vitamin D levels may play a role in facilitating implantation. Even in studies in vitro fertilization has been shown to increase the success rate with the support of vitamin D. In this article, vitamin D deficiency and infertility issues were revised in light of the current articles.