Development of a cost-effective glucose-corn steep medium for production of butanol by Clostridium beijerinckii

Parekh, Manish; Formanek, Joseph; Blaschek, Hans P.

doi:10.1038/sj.jim.2900569

Cited by 38 publications

(20 citation statements)

References 14 publications

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“…Studies with C. beijerinckii BA101 suggest that the developed strain is stable and can be used in a commercial fermentation process for producing butanol from glucose and cornstarch [5,6]. However, like other butanol-producing microorganisms, butanol is toxic to C. beijerinckii BA101.…”

Section: Introductionmentioning

confidence: 99%

Improving performance of a gas stripping-based recovery system to remove butanol from Clostridium beijerinckii fermentation

Ezeji

Karcher

Qureshi

et al. 2005

Bioprocess Biosyst Eng

149

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The effect of factors such as gas recycle rate, bubble size, presence of acetone, and ethanol in the solution/broth were investigated in order to remove butanol from model solution or fermentation broth (also called acetone butanol ethanol or ABE or solvents). Butanol (8 g L(-1), model solution, Fig. 2) stripping rate was found to be proportional to the gas recycle rate. In the bubble size range attempted (< 0.5 and 0.5-5.0 mm), the bubble size did not have any effect on butanol removal rate (Fig. 3, model solution). In Clostridium beijerinckii fermentation, ABE productivity was reduced from 0.47 g L(-1) h(-1) to 0.25 g L(-1) h(-1) when smaller (< 0.5 mm) bubble size was used to remove ABE (Fig. 4, results reported as butanol/ABE concentration). The productivity was reduced as a result of addition of an excessive amount of antifoam used to inhibit the production of foam caused by the smaller bubbles. This suggested that the fermentation was negatively affected by antifoam.

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Section: Introductionmentioning

confidence: 99%

Improving performance of a gas stripping-based recovery system to remove butanol from Clostridium beijerinckii fermentation

Ezeji

Karcher

Qureshi

et al. 2005

Bioprocess Biosyst Eng

149

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show abstract

“…In addition to the above studies, C. beijerinckii BA101 has been used in pilot plant reactors fed with corn steep liquor (CSL), a commercially rich nutrient source [4,5]. CSL is a product of the corn wet-milling process.…”

Section: Introductionmentioning

confidence: 99%

“…2 Materials and methods 2.1 Fermentation, substrate, plant size, and product recovery Batch [4,5], fed-batch [8], and immobilized-cell [9] fermentations were evaluated in the present studies. The medium contained CSL, which is an inexpensive nutrient source.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of recent advances in butanol fermentation, upstream, and downstream processing

Qureshi

Blaschek

2001

Bioprocess and Biosystems Engineering

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Four different processes for butanol production from corn, namely, batch fermentation and distillative recovery (BFDR), batch fermentation and pervaporative recovery (BFPR), fed-batch fermentation and pervaporative recovery (FBFPR), and immobilized cell continuous fermentation and pervaporative recovery (ICCFPR) were evaluated. Pervaporative recovery signi®cantly reduces the cost of butanol production. Depending upon the byproduct credit, which is approximately 3.7 times that of the amount of butanol produced, BFDR, BFPR, FBFPR, and ICCFPR result in a butanol price of $0.55, $0.14±0.39, $0.12±0.37, and $0.11±0.36´kg ±1 , respectively. The price of butanol was recently reported at $1.21´kg ±1 by Chemical Marketing Reporter. It should be noted that all three components (acetone, butanol, and ethanol: ABE) diffuse through the pervaporation membrane. Further separation and puri®cation of the solvents would require distillation, which has been considered in this exercise. This article also details the impact of byproduct credit, rate of return, and tax on butanol price.

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“…In the analysis process, (NH) 4 SO 4 was used as the less important factor. According to SS, P and E, the significance of nutrients could be ranked as CaCO 3 3 displayed a positive effect on butanol production. The variables with confidence levels greater than 95% were considered as influencing butanol production significantly.…”

Section: Effect Of Supplemental Nutrients In Butanol Productionmentioning

confidence: 99%

“…Researches have been intensified towards the production of alternative fuels such as butanol by fermentation [1]. Because butanol is not only an excellent feedstock chemical (in the plastic industry), a food-grade extractant (in the food and flavor industry), but also a replacement for gasoline as a fuel, a superior fuel to ethanol for higher energy content and safety [2][3][4][5]. Butnaol fermentation by the anaerobic bacterium Clostridium.…”

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confidence: 99%

Optimization of butanol production from corn straw hydrolysate by Clostridium acetobutylicum using response surface method

Lin

Wang

et al. 2011

Chin. Sci. Bull.

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Butanol is a new kind of very potential biofuels. Enzymatic hydrolysis of corn stalk was utilized in this study to produce butanol by Clostridium acetobutylicum CICC 8008. Plackett-Burman (P-B) design and Central Composite Design (CCD) were adopted to screen crucial factors during fermentation as well as the optimization of experimental conditions. The result demonstrated that among the seven factors, namely, Yeast extract, (NH 4 ) 2 SO 4 , KH 2 PO 4 , MgSO 4 , FeSO 4 , CuSO 4 and CaCO 3 , only CaCO 3 was selected as the most critical factor. The optimization experiment results for CaCO 3 usage, temperature and reaction time by CCD were determined to be 5.04 g/L, 35°C and 70 h, respectively. A corresponding mathematical model was established to predict the fermentation experiment and maximum butanol yield of 6.57 g/L was acquired. The result of verification experiment under the optimum conditions showed that 6.20 g/L was the maximum butanol yield. This demonstrated that statistical method was a powerful tool for the optimization of butanol production from enzymatic hydrolysis of corn stalk. Lin Y S, Wang J, Wang X M, et al. Optimization of butanol production from corn straw hydrolysate by Clostridium acetobutylicum using response surface method.

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Development of a cost-effective glucose-corn steep medium for production of butanol by Clostridium beijerinckii

Cited by 38 publications

References 14 publications

Improving performance of a gas stripping-based recovery system to remove butanol from Clostridium beijerinckii fermentation

Improving performance of a gas stripping-based recovery system to remove butanol from Clostridium beijerinckii fermentation

Evaluation of recent advances in butanol fermentation, upstream, and downstream processing

Optimization of butanol production from corn straw hydrolysate by Clostridium acetobutylicum using response surface method

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