Manipulation of heavy objects in industries is very necessary, but manual manipulation is tedious, adversely affects a worker’s health and safety, and reduces efficiency. On the contrary, autonomous robots are not flexible to manipulate heavy objects. Hence, we proposed human–robot systems, such as power assist systems, to manipulate heavy objects in industries. Again, the selection of appropriate control methods as well as inclusion of human factors in the controls is important to make the systems human friendly. However, existing power assist systems do not address these issues properly. Hence, we present a 1-DoF (degree of freedom) testbed power assist robotic system for lifting different objects. We also included a human factor, such as weight perception (a cognitive cue), in the robotic system dynamics and derived several position and force control strategies/methods for the system based on the human-centric dynamics. We developed a reinforcement learning method to predict the control parameters producing the best/optimal control performance. We also derived a novel adaptive control algorithm based on human characteristics. We experimentally evaluated those control methods and compared the system performance between the control methods. Results showed that both position and force controls produced satisfactory performance, but the position control produced significantly better performance than the force controls. We then proposed using the results to design control methods for power assist robotic systems for handling large and heavy materials and objects in various industries, which may improve human–robot interactions (HRIs) and system performance.