2007
DOI: 10.1016/j.clinbiochem.2007.03.024
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Development of a novel microarray methodology for the study of SNPs in the promoter region of the TNF-α gene—Their association with obstructive pulmonary disease in Greek patients

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Cited by 20 publications
(13 citation statements)
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“…Another two studies on COPD found an association of the haplotype containing the -863A variant with a lower risk for susceptibility to COPD, one performed on a Greek population [35] and the second performed on a Caucasian one [14]. Similarly, in our study the only haplotype that contains the -863A allele also tended to be less likely in COPD patients.…”
Section: Discussionsupporting
confidence: 75%
“…Another two studies on COPD found an association of the haplotype containing the -863A variant with a lower risk for susceptibility to COPD, one performed on a Greek population [35] and the second performed on a Caucasian one [14]. Similarly, in our study the only haplotype that contains the -863A allele also tended to be less likely in COPD patients.…”
Section: Discussionsupporting
confidence: 75%
“…This study is difficult to interpret as a third of the men were “never smokers”. Subsequent studies have found little evidence that TNF polymorphisms are associated with or modify the progression of COPD 42 47 5968…”
Section: Inflammationmentioning
confidence: 99%
“…Among all the included studies, six (Kuçukaycan et al, 2002;Brogger et al, 2006;Papatheodorou et al, 2007;Gingo et al, 2008;Gong et al, 2008;Trajkov et al, 2009) assessed the association of COPD risk with the -238 polymorphism in the TNF-α gene, while the other four (Papatheodorou et al, 2007;Gingo et al, 2008;Chen et al, 2010;Bi et al, 2011) with the -863 polymorphism. Since both of the two polymorphisms were assessed in two articles (Papatheodorou et al, 2007;Gingo et al, 2008), each article was considered to consist of two studies. Among the studies for the -238 polymorphism, one (Gong et al, 2008) was published in Chinese, with the others in English.…”
Section: Study Characteristicsmentioning
confidence: 99%
“…Eight articles (Kucukaycan et al, 2002;Brogger et al, 2006;Papatheodorou et al, 2007;Gingo et al, 2008;Gong et al, 2008;Trajkov et al, 2009;Chen et al, 2010;Bi et al, 2011) with ten eligible studies met the inclusion criteria. Among all the included studies, six (Kuçukaycan et al, 2002;Brogger et al, 2006;Papatheodorou et al, 2007;Gingo et al, 2008;Gong et al, 2008;Trajkov et al, 2009) assessed the association of COPD risk with the -238 polymorphism in the TNF-α gene, while the other four (Papatheodorou et al, 2007;Gingo et al, 2008;Chen et al, 2010;Bi et al, 2011) with the -863 polymorphism.…”
Section: Study Characteristicsmentioning
confidence: 99%
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