Development of a Parent-Proxy Quality-of-Life Chronic Cough-Specific Questionnaire

Newcombe, Peter; Sheffield, Jeanie; Juniper, Elizabeth F.; Marchant, Julie M.; Halsted, Ria A.; Masters, I. B.; Chang, Anne B.

doi:10.1378/chest.07-0888

Cited by 69 publications

(61 citation statements)

References 25 publications

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“…Generic health-related (PedsQL [17]) and chronic cough-specific (PC-QoL) QoL scores of children with PBB were found to be similar to those recorded in children from other diagnostic groups (asthma, bronchiectasis and those whose chronic cough resolved without treatment) when the QoL measures were undertaken at the first presentation to respiratory specialists [7,18], but normalised when the cough resolved [7].…”

Section: Introductionmentioning

confidence: 86%

ERS statement on protracted bacterial bronchitis in children

et al. 2017

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This European Respiratory Society statement provides a comprehensive overview on protracted bacterial bronchitis (PBB) in children. A task force of experts, consisting of clinicians from Europe and Australia who manage children with PBB determined the overall scope of this statement through consensus. Systematic reviews addressing key questions were undertaken, diagrams in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement constructed and findings of relevant studies summarised. The final content of this statement was agreed upon by all members.The current knowledge regarding PBB is presented, including the definition, microbiology data, known pathobiology, bronchoalveolar lavage findings and treatment strategies to manage these children. Evidence for the definition of PBB was sought specifically and presented. In addition, the task force identified several major clinical areas in PBB requiring further research, including collecting more prospective data to better identify the disease burden within the community, determining its natural history, a better understanding of the underlying disease mechanisms and how to optimise its treatment, with a particular requirement for randomised controlled trials to be conducted in primary care.This article has supplementary material available from

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Section: Introductionmentioning

confidence: 86%

ERS statement on protracted bacterial bronchitis in children

et al. 2017

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“…Ten of them were validation studies concerning cough frequency monitoring in children and/or adults [12,13,14,15,16,17,18,19,20,21]. Seven studies validating cough-specific quality-of-life scores were included [22,23,24,25,26,27,28,29]. …”

Section: Resultsmentioning

confidence: 99%

“…The Cough Quality of Life Questionnaire (CQLQ) was developed and validated in English [26,28,29]. One scale has been validated in the parents of children suffering from chronic cough in Australia [27], and 1 scale was developed and validated in Italian [23,24]. …”

Section: Resultsmentioning

confidence: 99%

“…Quality-of-life scales have been validated in adults with chronic cough and in the close relatives of children suffering from chronic cough and can thus be usefully applied in this context [25,26,27]. Further studies could evaluate the impact of cough under acute conditions.…”

Section: Discussionmentioning

confidence: 99%

“…Quality-of-life questionnaires should probably be used as primary outcome measures in trials of cough suppressants. There are 2 validated instruments for use in adults (LCQ [25] and CQLQ [26]) and 1 for use in children [27]. If cough frequency can be considered an indicator of disease severity, it can be used to monitor the evolution of the disease in terms of the treatment.…”

Section: Discussionmentioning

confidence: 99%

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Validated Methods of Cough Assessment: A Systematic Review of the Literature

et al. 2010

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Background: Cough is a common symptom for which patients often seek medical advice and consume vast amounts of drugs. It is a real challenge for both the physician and the clinical researcher to evaluate a cough’s clinical importance and its precise response to treatment. Objectives: This systematic literature review has the following objectives: first, to make an inventory of the validated tools for assessing cough, and second, to investigate the extent to which the results of various assessment methods can be correlated. Methods: Two independent investigators searched the Medline, Embase, and Cochrane databases for validation studies on cough assessment tools. Results: Thirty-four studies were included. Several ambulatory cough monitors automatically identify cough and have been validated in a limited number of patients. Three cough-specific quality-of-life scales (Leicester Cough Questionnaire, Cough Quality of Life Questionnaire, and Burden of Cough Questionnaire) have been validated. No validation studies of descriptive scores or visual analogue scales were found. The correlations between quality-of-life scores and cough frequency were good. The correlations between descriptive scores or visual analogue scales and more objective methods, such as cough frequency monitoring or quality-of-life scores, were inconsistent. Conclusion: Cough-specific quality-of-life questionnaires can provide valid outcomes for research into cough. Although the current developments in cough monitoring devices are promising, further studies on a larger scale, under more realistic conditions, and for different patterns of cough are required before they can be recommended for widespread use.

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Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults

Chang

Lasserson

Gaffney

et al. 2011

Cochrane Database of Systematic Reviews

162

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PPI is not efficacious for cough associated with GORD symptoms in very young children (including infants) and should not be used for cough outcomes. There is insufficient data in older children to draw any valid conclusions. In adults, there is insufficient evidence to conclude definitely that GORD treatment with PPI is universally beneficial for cough associated with GORD. Clinicians should be cognisant of the period (natural resolution with time) and placebo effect in studies that utilise cough as an outcome measure. Future paediatric and adult studies should be double-blind, randomised controlled and parallel-design, using treatments for at least two months, with validated subjective and objective cough outcomes and include ascertainment of time to respond as well as assessment of acid and/or non-acid reflux.

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Development of a Parent-Proxy Quality-of-Life Chronic Cough-Specific Questionnaire

Cited by 69 publications

References 25 publications

ERS statement on protracted bacterial bronchitis in children

ERS statement on protracted bacterial bronchitis in children

Validated Methods of Cough Assessment: A Systematic Review of the Literature

Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults

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