Development of a soft tissue seal around bone-anchored transcutaneous amputation prostheses

Pendegrass, CJ; Goodship, Allen E.; Blunn, Gordon

doi:10.1016/j.biomaterials.2006.03.041

Cited by 135 publications

(192 citation statements)

References 25 publications

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“…Traditional bone-anchored devices have suffered from a high rate of infection and chronic inflammation necessitating explantation [15], [16]. Pendegrass et al [13] have demonstrated a bone-anchored device design with a robust skin-implant seal, which was clinically successful in a trans-humeral amputee [11]. A modification of this implant was used in our experiment.…”

Section: Discussionmentioning

confidence: 99%

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The Use of a Bone-Anchored Device as a Hard-Wired Conduit for Transmitting EMG Signals From Implanted Muscle Electrodes

Al-Ajam

Lancashire

Pendegrass

et al. 2013

IEEE Trans. Biomed. Eng.

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Abstract-The use of a bone-anchored device to transmit electrical signals from internalised muscle electrodes was studied in a sheep model. The bone-anchored device was used as a conduit for the passage of a wire connecting an internal epimysial electrode to an external signal-recording device. The boneanchored device was inserted into an intact tibia and the electrode attached to the adjacent M. peroneus tertius. 'Physiological' signals with low signal to noise ratios were successfully obtained over a 12-week period by walking the sheep on a treadmill. Reliable transmission of multiple muscle signals across the skin barrier is essential for providing intuitive, biomimetic upper-limb prostheses. This technology has the potential to provide a better functional and reliable solution for upper-limb amputee rehabilitation: attachment and control.

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Section: Discussionmentioning

confidence: 99%

“…1. ) as described by Pendegrass et al [13]. A straight 2 mm hole was drilled from the top surface of the device, exiting immediately within the soft tissues above the region of the implant associated with osseointegration, this eliminated the need for an additional hole in the tibial cortex.…”

Section: A Bone-anchored / Electrode Device Constructionmentioning

confidence: 99%

The Use of a Bone-Anchored Device as a Hard-Wired Conduit for Transmitting EMG Signals From Implanted Muscle Electrodes

Al-Ajam

Lancashire

Pendegrass

et al. 2013

IEEE Trans. Biomed. Eng.

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“…Advances have been made in the integration of prosthetic devices to both the bony skeleton and the skin most noticeably in the UK with the intraosseous transcutaneous amputation prosthesis [73,74]. Perhaps, the final boundary is an implantable medical device within the peripheral nerves acting as an interface with a functioning prosthetic limb?…”

Section: Heterotopic Ossificationmentioning

confidence: 99%

Shaping the military wound: issues surrounding the reconstruction of injured servicemen at the Royal Centre for Defence Medicine

Evriviades

Jeffery

Cubison³

et al. 2011

Phil. Trans. R. Soc. B

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The conflict in Afghanistan has produced injuries similar to those produced from military conflicts for generations. What distinguishes the modern casualty of the conflict in Afghanistan from those of other conflicts is the effectiveness of modern field medical care that has led to individuals surviving with injuries, which would have been immediately fatal even a few years ago. These patients present several challenges to the reconstructive surgeon. These injured individuals present early challenges of massive soft-tissue trauma, unstable physiology, complex bony and soft-tissue defects, unusual infections, limited reconstructive donor sites, peripheral nerve injuries and traumatic amputations. Late challenges to rehabilitation include the development of heterotopic ossification in amputation stumps. This paper outlines the approach taken by the reconstructive team at the Royal Centre for Defence Medicine in managing these most difficult of reconstructive challenges.

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“…Pendegrass and colleagues tested a solid core with a porous flange positioned in the dermal tissues immediately below the epithelium [12][13]. Reduced mobility of skin in the plane parallel to the mesh collar or porous flange was reported.…”

Section: Introductionmentioning

confidence: 99%

Porous composite prosthetic pylon for integration with skin and bone

Pitkin¹,

Raykhtsaum²,

Pilling³

et al. 2007

JRRD

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Abstract-This article presents results of the further development and testing of the "skin and bone integrated pylon" (SBIP-1) for percutaneous (through skin) connection of the residual bone with an external limb prosthesis. We investigated a composite structure (called the SBIP-2) made of titanium particles and fine wires using mathematical modeling and mechanical testing. Results showed that the strength of the pylon was comparable with that of anatomical bone. In vitro and in vivo animal studies on 30 rats showed that the reinforcement of the composite pylon did not compromise its previously shown capacity for inviting skin and bone cell ingrowth through the device. These findings provide evidence for the safe and reliable long-term percutaneous transfer of vital and therapeutic substances, signals, and necessary forces and moments from a prosthetic device to the body.

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Development of a soft tissue seal around bone-anchored transcutaneous amputation prostheses

Cited by 135 publications

References 25 publications

The Use of a Bone-Anchored Device as a Hard-Wired Conduit for Transmitting EMG Signals From Implanted Muscle Electrodes

The Use of a Bone-Anchored Device as a Hard-Wired Conduit for Transmitting EMG Signals From Implanted Muscle Electrodes

Shaping the military wound: issues surrounding the reconstruction of injured servicemen at the Royal Centre for Defence Medicine

Porous composite prosthetic pylon for integration with skin and bone

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