Development of an Electrowetting Digital Microfluidics Platform using Low-cost Materials

Meimandi, Ali; Seyedsadrkhani, Niloofar; Jahanshahi, Amir

doi:10.1109/iraniancee.2019.8786395

Cited by 5 publications

(6 citation statements)

References 8 publications

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“…Similar platforms have been reported for biological application and lower driven voltages, about AC voltage of 200 V at 1 kHz, for moving droplets of about 30 µL [55]. Besides, the works reported in [56] moved droplets of about 10 µL with a speed of 3 mm/s by applying a high DC voltage, 400 V. This very low cost device is composed of a planar array of six electrodes with silicone rubber as the dielectric layer and a commercially available water repellent as the hydrophobic layer. A similar open platform was reported in [57]; a planar array of 64 electrodes was developed.…”

Section: Electrowetting On Dielectricsupporting

confidence: 77%

“…Low-cost, coreless, PCB-based transformers for signal and low-power applications have been proposed [55]. Regarding the use of the core, there are other developments [56,57], but additional materials are required, typically ferrite. In addition, these two last developments use a multiple-PCB structure to fabricate the transformers.…”

Section: Transformers and Motorsmentioning

confidence: 99%

“…The primary and secondary windings are fabricated using the two copper layers of a double-layer PCB [58][59][60][61][62][63], although there are developments using multiple layers (four layers) PCBs [56,64]. In the first case, the FR4 layer offers an electrical isolation ranging between 15 and 40 kV.…”

Section: Transformers and Motorsmentioning

confidence: 99%

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Lab-on-PCB Devices

2022

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Section: Electrowetting On Dielectricsupporting

confidence: 77%

Section: Transformers and Motorsmentioning

confidence: 99%

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Lab-on-PCB Devices

2022

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“…Similar platforms have been reported for biological application and lower driven voltages, about AC voltage of 200 V at 1 kHz, for moving droplets of about 30

L [ 55 ]. Besides, the works reported in [ 56 ] moved droplets of about 10

L with a speed of 3 mm/s by applying a high DC voltage, 400 V. This very low cost device is composed of a planar array of six electrodes with silicone rubber as the dielectric layer and a commercially available water repellent as the hydrophobic layer. A similar open platform was reported in [ 57 ]; a planar array of 64 electrodes was developed.…”

Section: Electrowetting On Dielectricmentioning

confidence: 99%

Lab-on-PCB and Flow Driving: A Critical Review

Perdigones

2021

Micromachines

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Lab-on-PCB devices have been developed for many biomedical and biochemical applications. However, much work has to be done towards commercial applications. Even so, the research on devices of this kind is rapidly increasing. The reason for this lies in the great potential of lab-on-PCB devices to provide marketable devices. This review describes the active flow driving methods for lab-on-PCB devices, while commenting on their main characteristics. Among others, the methods described are the typical external impulsion devices, that is, syringe or peristaltic pumps; pressurized microchambers for precise displacement of liquid samples; electrowetting on dielectrics; and electroosmotic and phase-change-based flow driving, to name a few. In general, there is not a perfect method because all of them have drawbacks. The main problems with regard to marketable devices are the complex fabrication processes, the integration of many materials, the sealing process, and the use of many facilities for the PCB-chips. The larger the numbers of integrated sensors and actuators in the PCB-chip, the more complex the fabrication. In addition, the flow driving-integrated devices increase that difficulty. Moreover, the biological applications are demanding. They require transparency, biocompatibility, and specific ambient conditions. All the problems have to be solved when trying to reach repetitiveness and reliability, for both the fabrication process and the working of the lab-on-PCB, including the flow driving system.

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“…With the rapid development of electronics manufacturing industry, the PCB manufacturing industry has a unified and standardized manufacturing facility and process [7]. Moreover, it has the characteristics of low cost and high integration, which is suitable for making EWOD devices [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Design of an Open Electrowetting on Dielectric Device Based on Printed Circuit Board by Using a Parafilm M

Feng

Zhou

et al. 2020

Front. Phys.

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In recent years, the open electrowetting on dielectric (EWOD) device has been widely used in biomedical detection, chemical synthesis analysis, and so on. However, the cost of using ITO glass as surface material is difficult to meet the requirement for large-scale array chip production. So, a low-cost, easy-to-manufacture open EWOD platform is designed in this paper. In hardware platform, an operation platform is prepared by using a printed circuit board (PCB) as a substrate. The electrode shape is designed as zigzag, and its surface is optimized by organic solderability preservatives (OSP). In addition, Parafilm M and silicone oil are used as a dielectric hydrophobic layer to prepare the open platform. In software, the system program is designed by C programming language, including initialization program, serial port communication program, high-voltage output port program, and interrupt program, which can be used to drive droplets. The system can achieve an effective driving voltage of 180-240 V. The moving speed of droplets can reach 15 mm/s when the droplet volume is 1850 µL and the electrode voltage output frequency is 10 Hz.

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Development of an Electrowetting Digital Microfluidics Platform using Low-cost Materials

Cited by 5 publications

References 8 publications

Lab-on-PCB Devices

Lab-on-PCB Devices

Lab-on-PCB and Flow Driving: A Critical Review

Design of an Open Electrowetting on Dielectric Device Based on Printed Circuit Board by Using a Parafilm M

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