The COVID-19 pandemic outbreak has created a new complicated reality and brought diverse challenges to education systems and students as well. The present study aimed at examining the factors that students have used in identifying career choices among Palestinian high school in Israel in the new era. Career choice questionnaire was used to assess the factors affecting career choice. 455 Palestinian high school students took part in this study. A convenient sampling technique was implied to collect the data. Descriptive statistics, t-test, one-way ANOVA were used to analyze the data. Findings revealed that the student’s interests and hobbies, and student’s personality and tendencies attained the highest value among the internal factors of career choice. Furthermore, the future progress and advancement opportunities, job security were the prominent external factors. Findings showed that the internal factors were significantly associated with economic situation. The findings will assist school counselors to raise the self-awareness to the importance of the internal and external factors, thus students may make better future career decisions.