Development of Bioaerosol Alarming Detector

Wuijckhuijse, AL van; Kientz, Ch.E.; Baar, Ben van; Kievit, O.; Busker, R.W.; Stowers, M.A.; Kleefsman, W.A.; Marijnissen, J.C.M.

doi:10.1007/1-4020-3384-2_9

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…This matrix effect in the laser desorption studies is still misinterpreted and under discussion [8,40]. Thomson et al (1997) suggested that the energetic level necessary to obtain an ion production of a constituent strongly depends on other compounds present within the particle under analysis [39].…”

Section: Discussionmentioning

confidence: 99%

Development of an analytical methodology for obtaining quantitative mass concentrations from LAAP-ToF-MS measurements

Gemayel

Temime-Roussel

Hayeck

et al. 2017

Talanta

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Laser ablation aerosol particle-time of flight mass spectrometer (LAAP-ToF-MS) measures the size number of particles, and chemical composition of individual particles in real-time. LAAP-ToF-MS measurements of chemical composition are difficult to quantify, mostly because the instrument sensitivities to various chemical species in the multicomponent atmospheric aerosol particles are unknown. In this study, we investigate a field-based approach for quantitative measurements of ammonium, nitrate, sulfate, OC, and EC, in size-segregated atmospheric aerosols, by LAAP-ToF-MS using concurrent measurements from high-resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS), and multi-angle absorption photometer (MAAP). An optical particle counter (OPC) and a high-resolution nanoparticle sizer (scanning mobility particle sizer, or SMPS), were used to measure the particle size distributions of the particles in order to correct the number concentrations. The intercomparison reveals that the degree of agreement of the mass concentrations of each compound measured with LAAP-ToF-MS and HR-ToF-AMS/MAAP increases in the following order NH < SO < NO < EC < OC < Cl with r values in the range of 0.4-0.95 and linear regression slopes ranging between 0.62 and 1.2. The factors that affect the mass concentrations measured by LAAP-ToF-MS are also discussed in details. Yet, the matrix effect remains one of the strongest limiting factor to achieve an absolute quantification of the aerosol chemical composition. In the future we suggest the development of a methodology based on the calculation of the response factors generated by different types of particles, which could possibly resolve certain difficulties associated with the matrix effect.

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Section: Discussionmentioning

confidence: 99%

Development of an analytical methodology for obtaining quantitative mass concentrations from LAAP-ToF-MS measurements

Gemayel

Temime-Roussel

Hayeck

et al. 2017

Talanta

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Recent Advances in Real-time Mass Spectrometry Detection of Bacteria

Wuijckhuijse

Baar

2008

Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems

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The analysis of bio-aerosols poses a technology challenge, particularly when sampling and analysis are done in situ. Mass spectrometry laboratory technology has been modified to achieve quick bacteria typing of aerosols in the field. Initially, aerosol material was collected and subjected off-line to minimum sample treatment and mass spectrometry analysis. More recently, sampling and analysis were combined in a single process for the real-time analysis of bio-aerosols in the field. This chapter discusses the development of technology for the mass spectrometry of bio-aerosols, with a focus on bacteria aerosols. Merits and drawbacks of the various technologies and their typing signatures are discussed. The chapter concludes with a brief view of future developments in bio-aerosol mass spectrometry.

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Development of Bioaerosol Alarming Detector

Cited by 2 publications

References 10 publications

Development of an analytical methodology for obtaining quantitative mass concentrations from LAAP-ToF-MS measurements

Development of an analytical methodology for obtaining quantitative mass concentrations from LAAP-ToF-MS measurements

Recent Advances in Real-time Mass Spectrometry Detection of Bacteria

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