Development of carrier-free self-assembled nanoparticles based on fenhexamid and polyhexamethylene biguanide for sustainable plant disease management

Tang, Gang; Tian, Yuyang; Niu, Junfan; Tang, Jianzhao; Yang, Jiale; Gao, Yunhao; Chen, Xi; Li, Xuan; Wang, Huachen; Cao, Yongsong

doi:10.1039/d1gc00006c

Cited by 44 publications

(24 citation statements)

References 59 publications

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“…Concerning the antibacterial activity, no tests were conducted for any of the NCs presented in Table 4, but it is worth noting that the MIC value attained against P. syringae for the ML-COS NCs loaded with R. tinctorum extract (37.5 µg•mL −1 ) was substantially lower than, for instance, the one reported by Tang et al [43] (MIC = 106.25 µg•mL −1 ) for self-assembled nanoparticles based on polyhexa-methylene biguanide (PHMB) and fenhexamid (FHA) fungicide against Pseudomonas syringae pv. lachrymans.…”

Section: Comparison With Other Ncs-based Treatmentsmentioning

confidence: 80%

Lignin–Chitosan Nanocarriers for the Delivery of Bioactive Natural Products against Wood-Decay Phytopathogens

et al. 2022

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The use of nanocarriers (NCs), i.e., nanomaterials capable of encapsulating drugs and releasing them selectively, is an emerging field in agriculture. In this study, the synthesis, characterization, and in vitro and in vivo testing of biodegradable NCs loaded with natural bioactive products was investigated for the control of certain phytopathogens responsible for wood degradation. In particular, NCs based on methacrylated lignin and chitosan oligomers, loaded with extracts from Rubia tinctorum, Silybum marianum, Equisetum arvense, and Urtica dioica, were first assayed in vitro against Neofusicoccum parvum, an aggressive fungus that causes cankers and diebacks in numerous woody hosts around the world. The in vitro antimicrobial activity of the most effective treatment was further explored against another fungal pathogen and two bacteria related to trunk diseases: Diplodia seriata, Xylophilus ampelinus, and Pseudomonas syringae pv. syringae, respectively. Subsequently, it was evaluated in field conditions, in which it was applied by endotherapy for the control of grapevine trunk diseases. In the in vitro mycelial growth inhibition tests, the NCs loaded with R. tinctorum resulted in EC90 concentrations of 65.8 and 91.0 μg·mL−1 against N. parvum and D. seriata, respectively. Concerning their antibacterial activity, a minimum inhibitory concentration of 37.5 μg·mL−1 was obtained for this treatment against both phytopathogens. Upon application via endotherapy on 20-year-old grapevines with clear esca and Botryosphaeria decay symptoms, no phytotoxicity effects were observed (according to SPAD and chlorophyll fluorescence measurements) and the sugar content of the grape juice was not affected either. Nonetheless, the treatment led to a noticeable decrease in foliar symptoms as well as a higher yield in the treated arms as compared to the control arms (3177 vs. 1932 g/arm), suggestive of high efficacy. Given the advantages in terms of controlled release and antimicrobial product savings, these biodegradable NCs loaded with natural extracts may deserve further research in large-scale field tests.

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Section: Comparison With Other Ncs-based Treatmentsmentioning

confidence: 80%

Lignin–Chitosan Nanocarriers for the Delivery of Bioactive Natural Products against Wood-Decay Phytopathogens

et al. 2022

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“…The regions rich in mineral nutrients from deeper porous zones are hard to reach due to constricted plant root anatomy that make them incapable of achieving the root length required for harvesting nutrients. In deep hard areas, the phenomenon like evaporation, and high transpiration rates dehydrate the plant leading to reduction in porosity and cysts generation ( Tang et al., 2021 a). The Pseudomonas and its associated PGPR induce root stimulation resulting in elongation to promote plant-mineral feedback mechanism by mutualistic cooperation.…”

Section: Pseudomonas Mediated Establishment Of Rhizospheric Competencymentioning

confidence: 99%

Pseudomonas mediated nutritional and growth promotional activities for sustainable food security

Sah

Krishnani

Singh

2021

Current Research in Microbial Sciences

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Highlights Fluorescent and non-fluorescent species of Pseudomonas are important for plant growth promotion, phytopathogenic control and plant disease management. Pseudomonas belong to Pseudomonadaceae family (10 groups on the basis of rRNA-DNA hybridization) classified into 6-subgroups of rRNA gene homology and RFLP. Pseudomonas species produce antagonistic mechanism such as ISR and compounds like cell wall degradation enzymes, and antibiotics to maintain a mutualistic relationship with the associated plant. Pseudomonas sp. synthesize auxins having properties similar to phytohormones like IAA, which act as signaling molecules for regulating plant growth.

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“…Nanocarriers with good biocompatibility have been applied extensively in promoting the translocation of drugs across cell membranes for disease treatment. , Similar to medical therapy, some nanoparticles have been used to construct a pesticide delivery system in recent years, and the controlled release of active ingredients (AIs) is particularly important to obtain the maximum biological efficacy and decrease the negative environmental impacts. − Generally, many kinds of adjuvants such as organic solvents, emulsifiers, and dispersants are added to commercial pesticides to increase their biological activity, and large proportions of sprayed pesticides are lost due to photolysis, surface runoff, and spray drift, thus leading to serious environmental pollution and threatening human health. − The AIs of most traditional pesticides are hydrophobic, and the AIs can be encapsulated in nanoparticles or attached to the peripheral groups of nanoparticles, which can increase the dispersion and wettability of AIs, and improve stability of AIs against harsh environmental conditions. − Our group has constructed a series of dendrimer-based nanoparticles consisting of a fluorescent core and periphery amino groups, which can act as a dsRNA/drug carrier to efficiently improve their delivery efficiency. − Furthermore, we construct a star polymer (SPc) without a fluorescent core for large-scale application, which is applied to produce nanoscale botanical/chemical insecticides and increase their insecticidal activity. , …”

Section: Introductionmentioning

confidence: 99%

Simple Osthole/Nanocarrier Pesticide Efficiently Controls Both Pests and Diseases Fulfilling the Need of Green Production of Strawberry

Yan

Jiang

et al. 2021

ACS Appl. Mater. Interfaces

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The application of botanical pesticides is a good choice in organic agriculture. However, most botanical pesticides have limitations of slow action and short persistence for pest and disease management, which constrain their further application. With the objective of exploring a green pesticide for controlling strawberry pests and diseases simultaneously, a star polymer (SPc) with a low production cost was synthesized as a pesticide nanocarrier through simple reactions. The SPc complexed with osthole quickly through electrostatic interaction and hydrophobic association, which decreased the particle size of osthole down to the nanoscale (17.66 nm). With the help of SPc, more nano-sized osthole was delivered into cytoplasm through endocytosis, leading to the enhanced cytotoxicity against insect cells. As a green botanical pesticide, the control efficacy of the osthole/SPc complex was improved against main strawberry pests (green peach aphid and two-spotted spider mite) and disease (powdery mildew), which fulfilled the need of both pest and disease management in sustainable production of strawberry. Meanwhile, the introduction of SPc not only improved plant-uptake but also decreased the residue of osthole due to the higher degradation rate. Furthermore, the application of the osthole/SPc complex exhibited no influence on the strawberry fruit quality and nontarget predators. To our knowledge, it is the first success to control plant pests and diseases simultaneously for sustainable agriculture by only one pesticidal formulation based on nanoparticle-delivered botanical pesticides.

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Development of carrier-free self-assembled nanoparticles based on fenhexamid and polyhexamethylene biguanide for sustainable plant disease management

Abstract: The utilization of nanotechnology for the design of pesticide formulations has enormous potential to enhance the efficiency of pesticides and reduce their adverse impacts on the environment

Cited by 44 publications

References 59 publications

Lignin–Chitosan Nanocarriers for the Delivery of Bioactive Natural Products against Wood-Decay Phytopathogens

Lignin–Chitosan Nanocarriers for the Delivery of Bioactive Natural Products against Wood-Decay Phytopathogens

Pseudomonas mediated nutritional and growth promotional activities for sustainable food security

Simple Osthole/Nanocarrier Pesticide Efficiently Controls Both Pests and Diseases Fulfilling the Need of Green Production of Strawberry

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