Development of<i>Pasteurella multocida-</i>loaded microparticles for hemorrhagic septicemia vaccine

Nimtrakul, Pataranapa; Atthi, Ratchanee; Limpeanchob, Nanteetip; Tiyaboonchai, Waree

doi:10.3109/03639045.2013.873448

Cited by 4 publications

(3 citation statements)

References 27 publications

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“…The Tiyaboonchai lab encapsulated Pasteurella multocida within alginate microparticles for subcutaneous injections. Key to this study was a 6‐month storage test, where antigenicity was investigated in samples kept either at 4 or 37 °C (Nimtrakul et al, 2015). Results revealed that mice injected with either formulation elicited an immune response similar to freshly encapsulated antigens.…”

Section: The Interaction Between Antigen and Biomaterialsmentioning

confidence: 99%

“…Encapsulation infiltration have been more heavily investigated owing to the potential stability they the antigens trapped within. Created with BioRender.com samples kept either at 4 or 37 C (Nimtrakul et al, 2015). Results revealed that mice injected with either formulation elicited an immune response similar to freshly encapsulated antigens.…”

Section: Antigenicity and Long-term Stabilitymentioning

confidence: 99%

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Biomaterials and nanomaterials for sustained release vaccine delivery

Luzuriaga

Shahrivarkevishahi

Herbert

et al. 2021

WIREs Nanomed Nanobiotechnol

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Vaccines are considered one of the most significant medical advancements in human history, as they have prevented hundreds of millions of deaths since their discovery; however, modern travel permits disease spread at unprecedented rates, and vaccine shortcomings like thermal sensitivity and required booster shots have been made evident by the COVID‐19 pandemic. Approaches to overcoming these issues appear promising via the integration of vaccine technology with biomaterials, which offer sustained‐release properties and preserve proteins, prevent conformational changes, and enable storage at room temperature. Sustained release and thermal stabilization of therapeutic biomacromolecules is an emerging area that integrates material science, chemistry, immunology, nanotechnology, and pathology to investigate different biocompatible materials. Biomaterials, including natural sugar polymers, synthetic polyesters produced from biologically derived monomers, hydrogel blends, protein–polymer blends, and metal–organic frameworks, have emerged as early players in the field. This overview will focus on significant advances of sustained release biomaterial in the context of vaccines against infectious disease and the progress made towards thermally stable “single‐shot” formulations. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Infectious Disease

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Section: The Interaction Between Antigen and Biomaterialsmentioning

confidence: 99%

Section: Antigenicity and Long-term Stabilitymentioning

confidence: 99%

Biomaterials and nanomaterials for sustained release vaccine delivery

Luzuriaga

Shahrivarkevishahi

Herbert

et al. 2021

WIREs Nanomed Nanobiotechnol

View full text Add to dashboard Cite

show abstract

“…In vitro assays have been performed using macrophages and aortic endothelial cells [348][349][350][351]. Mouse models can play an important role in investigation of pathogenesis and vaccine development [317,[351][352][353][354][355][356][357][358][359][360][361][362][363]. Rats with or without immunosuppression have also been used to explore pathogenesis and novel vaccines [349][350][351][364][365][366].…”

Section: Hemorrhagic Septicemiamentioning

confidence: 99%

Transboundary Animal Diseases, an Overview of 17 Diseases with Potential for Global Spread and Serious Consequences

Clemmons

Alfson

Dutton

2021

Animals

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Animals provide food and other critical resources to most of the global population. As such, diseases of animals can cause dire consequences, especially disease with high rates of morbidity or mortality. Transboundary animal diseases (TADs) are highly contagious or transmissible, epidemic diseases, with the potential to spread rapidly across the globe and the potential to cause substantial socioeconomic and public health consequences. Transboundary animal diseases can threaten the global food supply, reduce the availability of non-food animal products, or cause the loss of human productivity or life. Further, TADs result in socioeconomic consequences from costs of control or preventative measures, and from trade restrictions. A greater understanding of the transmission, spread, and pathogenesis of these diseases is required. Further work is also needed to improve the efficacy and cost of both diagnostics and vaccines. This review aims to give a broad overview of 17 TADs, providing researchers and veterinarians with a current, succinct resource of salient details regarding these significant diseases. For each disease, we provide a synopsis of the disease and its status, species and geographic areas affected, a summary of in vitro or in vivo research models, and when available, information regarding prevention or treatment.

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