Development of ionophore-based nanosphere emulsion incorporating ion-exchanger for complexometric titration of thiocyanate anion

Abstract

Graphical abstract

Benchmarking the placement of hydrosulfide in the Hofmeister series using a bambus[6]uril-based ChemFET sensor

“…Electrochemical potentiometric sensors, which incorporate simple instrumentation that is easily integrated with chip-based devices, 14,15 are one option for HS − detection. Potentiometric sensors interface different membrane designs with sensor components, including inorganic crystal lattices, 16 lipophilic ionophores, 17 or metal-ligand coordination to impart analyte selectivity. 18,19 The selectivity of an electrochemical sensor is derived from the membrane, and different components that impart selectivity can be incorporated into these membranes.…”

Ionophore-Based Nanosphere Emulsion Incorporating Ion-Exchanger for Picogram Potentiometric Determination of HCV Drug (Daclatasvir) in Pharmaceutical Formulations and Body Fluids

“…(10) Exploring the application of the method in clinical settings for therapeutic drug monitoring and pharmacokinetic studies. (11) Measuring drug concentrations in patient samples to optimize dosing regimens and improve outcomes. (12) Investigate automation and miniaturization possibilities by integrating the emulsion with automated systems or microfluidic devices.…”

“…Bakker's titration reagent is a suspension of nanospheres consisting of a lipophilic core (plasticizer) stabilized by an amphiphilic polymer material such as Pluronic F-127 (F-127) [2,7]. However, the literature cites the limited application of this ionophore-based emulsion in potentiometric titration, which has been confined to the determination of metal ions (Pb 2+ and Ca 2+ [2]) and inorganic anions (ClO 4 − , NO 3 − [7], and SCN − [11]). To our knowledge, no reports in the literature quantify bulky organic analytes using nanospherebased potentiometric titration.…”