Development of microbial protective Kolliphor‐based nanocomposite hydrogels

Abstract

In this scientific work, a novel class of antimicrobial nanocomposite hydrogels were designed and synthesized by chemical and environmentally bioprocess using Kolliphor, acrylamide, and mint leafs in order to achieve antiseptic property for wound applications. In the bioprocess approach, silver nitrate and gold chloride were nucleated with mint leafs in order to obtain effective free individual nano-inorganic compounds to provide superior antibacterial assets. The formations of dual inorganic nanoparticles were confirmed by transmission electron microscopy, which indicated the size of nanoparticles in the range of approximately 3 6 2 nm and without agglomeration. The formations of biomaterials were characterized using Fourier transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopic-energy dispersive spectrometric studies and their swelling properties were determined. Furthermore, the pure hydrogel and the dual inorganic nanocomposite hydrogels developed were tested for antibacterial activities. When compared with the neat hydrogel, the nanocomposite hydrogels significantly improved their anti-bacterial activities on Bacillus bacterium.

Natural Polysaccharide-Based Hydrogels Used for Dye Removal

“…Polymeric hydrogels have diverse applications across multiple fields, including medicine, cosmetics, agriculture, and materials science. In the medical sector, they play a crucial role in drug delivery systems [34], wound dressings [35], tissue engineering [36], or as agents with antibacterial properties [37]. Within cosmetics, polymeric hydrogels are employed into products such as gels, creams, and lotions to enhance texture and stability [38,39].…”

Hydrogel microrobots for biomedical applications

“… (2) Chemical Cross-linking: Gels synthesized through chemical cross-linking result from the covalent bonding of polymer chains, engendering a permanent network structure, hence their designation as irreversible gels ( Caló and Khutoryanskiy, 2015 ). Notable examples include whey protein ( Abaee et al, 2017 ), kolliphor ( Varaprasad and Sadiku, 2015 ), cellulose nanofiber ( Kobe et al, 2016 ), etc. The preparation of these chemically cross-linked gels typically involves a range of reactions, including photopolymerization ( Nezhad-Mokhtari et al, 2019 ), enzymatic processes ( Sperinde and Griffith, 1997 ), and click chemistry ( Liu et al, 2022 ), ensuring a robust and enduring gel framework.…”

The seepage flow characteristics of hydrophobically associated polymers with different aggregation behaviours in porous media

“…Micromorphology is analysed using an environmental scanning electron microscope [27,28]. The concrete steps are as follows: (i) configure a polymer solution into a target concentration solution; (ii) place a drop of polymer solution on the metal sample rack and fix it, use liquid nitrogen to solidify the solution quickly and lock the structure form in the solution, and then, sublimate the water molecule in the freeze vacuum dryer; (iii) a special device is used to cover the surface of the sample; (iv) observe the microstructure of the polymer solution using a scanning electron microscope.…”