This study aims to develop an electronics mathematics learning module (MLM) using SIGIL software in the form of ePUB3 which can be used to improve the statistical thinking skills of high school students in Medan, North Sumatra, Indonesia. This research is a research and development (R&D) study with an ASSURE design model consisting of 6 stages, including analyzing learners, state objectives; select methods, media and materials; util media and materials; require participant learner; evaluate and revise. At the product validation stage, ePUB3-eMLM can be applied in mathematics learning in the field. The results of the development of ePUB3-eMLM are implemented to three high schools with cluster types: accreditation school A, accreditation school B and accreditation school C. The implementation of ePUB3-ebook mathematics uses a flipped classroom model combined with a project-based learning model in the face-to-phase phase face learning. Based on the results of the development and implementation, it is obtained that ePUB3-eMLM that has been developed is valid and effective in improving the statistical thinking skills of high school students in Medan,