The paper describes the study of mechanical activation of multi-component ceramic powder materials based on boron nitride. The mechanical activation of the powders was carried out according to the best optimal parameters in a ball mill AGO-2U. Increasing the time of mechanical activation leads to more fine-grained powders. We described the technique of mechanical activation of ceramic powder materials. We introduced the results of X-ray diffraction analysis of the ceramic powder cBN, cBN-Co, hBN-Co before and after mechanical activation. We generated mathematical equations of dependence of an average powder particle size on the average mechanical activation time. We described how the crystal lattice "a" parameters and unit cell volume "V" of cBN and hBN powders depend on mechanical activation time. We studied the chemical composition of powder materials. We also studied the structural parameters of ceramic powders.