Development of screening systems for evaluation of materials used in mammalian embryo transfer

Lee, B.E.; Boone, William R.; Brackelsberg, Phyllis; Carmichael, R.A.

doi:10.1016/0093-691x(88)90210-5

Cited by 6 publications

(1 citation statement)

References 9 publications

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“…It is well documented that not all products, despite being packaged or sold as sterile, are inert in terms of impact on embryo development. 175,176 Thus, verification of material safety is required prior to clinical use. This is usually performed using a relevant bioassay, such as the mouse embryo assay (MEA) or the human sperm survival assay (HSSA), also known as the human sperm motility assay (HSMA).…”

Section: Culture Dishesmentioning

confidence: 99%

Optimal Human Embryo Culture

Swain

2015

Semin Reprod Med

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A large contributor to success during in vitro fertilization (IVF) lies in the processes occurring within the IVF laboratory. These processes make up the "culture system." This system entails numerous procedures and technical steps that must be optimized to produce a competent embryo. Notably, variations exist between programs that include differences in patient population, clinical stimulation, and other factors. Thus, a single "optimal" culture system to be utilized between all laboratories is likely not feasible. Rather, laboratory procedures should be optimized based on an individual laboratory's performance. That being said, within the scientific literature, there are key components, approaches, and techniques within the culture system that have been shown to be superior to alternatives. These key components important in improving embryo culture are discussed.

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Section: Culture Dishesmentioning

confidence: 99%