2022
DOI: 10.1007/s42770-022-00690-9
|View full text |Cite
|
Sign up to set email alerts
|

Development of sensitive and specific loop-mediated isothermal amplification combined with lateral flow device for the rapid detection of hepatitis B virus infection

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

1
1
0

Year Published

2023
2023
2023
2023

Publication Types

Select...
2
1

Relationship

0
3

Authors

Journals

citations
Cited by 3 publications
(2 citation statements)
references
References 21 publications
1
1
0
Order By: Relevance
“…This detection limit is acceptable for clinical diagnosis. However, this result is consistent with several studies that indicated they were able to detect a viral DNA load as low as 10 2 − 10 1 IU/ml by the LAMP reaction for HBV DNA from HBV-positive plasma [12,14,15,17,24]. The optimized approach possesses a false-negative rate of 33.4%, which is explicitly high.…”
Section: Discussionsupporting
confidence: 89%
“…This detection limit is acceptable for clinical diagnosis. However, this result is consistent with several studies that indicated they were able to detect a viral DNA load as low as 10 2 − 10 1 IU/ml by the LAMP reaction for HBV DNA from HBV-positive plasma [12,14,15,17,24]. The optimized approach possesses a false-negative rate of 33.4%, which is explicitly high.…”
Section: Discussionsupporting
confidence: 89%
“…Moreover, this device is compatible with microfluidic platforms and can be adapted for high throughput point-of-care diagnosis of HBV. In addition, Chen et al 80 and Maity et al 81 reported a LAMP based lateral flow device for the rapid detection of HBV infection. The entire detection process can be completed within 60 minutes, with a detection limit of 7.5 IU per test and a specificity of 100%.…”
Section: Loop-mediated Isothermal Amplification (Lamp)mentioning
confidence: 99%