The theoretical framework behind family-centered developmentally supportive care is endorsed by research from several scientific fields such as neuroscience, developmental and family psychology, medicine and nursing. The most developed and well-studied form of developmental care is the newborn individualized care and assessment program (NIDCAP). This program has been shown to reduce stress and pain behaviors, physiologic stress response and decrease the use of sedatives and opioids. In addition, NIDCAP has positive effects on pulmonary morbidity, brain lesions and costs in the newborn period. In the longer term, the program is also reported to improve cognitive outcome and behavior in former very low-birth weight infants. The introduction of NIDCAP is not a trivial process but involves a considerable investment at all levels of the organization. NIDCAP requires some physical changes in the neonatal intensive care unit as well as substantial educational efforts and changes in the practice of care. The findings of the presented NIDCAP studies are encouraging and, equally important, is attractive from an ethical and humane perspective.