Developments in ion chromatography using monolithic columns

Abstract

The focus of this review is on current status and on-going developments in ion chromatography (IC) using monolithic phases. The use and potential of both silica and polymeric monoliths in IC is discussed, with silica monoliths achieving efficiencies upwards of 10(5) plates/m for inorganic ions in a few minutes or less. Ion exchange capacity can be introduced onto the monolithic columns through the addition of ion interaction reagents to the eluent, coating of the monolith with ionic surfactants or polyelectrolyte latexes, and covalent bonding. The majority of the studies to date have used surfactant-coated columns, but the stability of surfactant coatings limits this approach. Applications of monolithic IC columns to the separation of inorganic anions and cations are tabulated. Finally, a discussion on the recent commercialization of monolithic IC columns and the use of monolithic phases for IC peripherals such as preconcentrator columns, microextractors and suppressors is presented.

Stationary phases for chromatography prepared by ring opening metathesis polymerization

“…In this approach one can use virtually any carrier that is suitable in terms of particle size, pore size distribution, and pore volume, e. g., silica, alumina, titania, or zirconia [32]. In principle, one can distinguish between dynamic and covalent coatings [33,34] supports is insoluble in the mobile phase that is to be used later. Typically, both poly(butadiene) and poly(ethylene) have been used to create nonpolar surfaces with RPcharacter [23,25].…”

Ion Chromatographic Analyses of Sea Waters, Brines and Related Samples

“…Nakatani et al presented an overview of one of more recent challenges of ion-exclusion/ion-exchange chromatography in determining simultaneously inorganic anions and cations [12]. Monolitic columns, which open up some new opportunities for ion chromatography, were also reviewed [13,14].…”

Rapid and Simultaneous Determination of Tetrafluoroborate, Thiocyanate and Hexafluorophosphate by High-Performance Liquid Chromatography Using a Monolithic Column and Direct Conductivity Detection

“…29,30 In recent years, the preparation and application of monolithic columns have been developed rapidly in capillary electrochromatography (CEC), HPLC and IC. [30][31][32][33][34][35] The main forms of monoliths are organic polymer monoliths and silica-based monoliths. In IC, there are two methods for anion separation using a silica-based monolithic column.…”