2009
DOI: 10.1002/cem.1242
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Deviations from linearity in statistical evaluation of linearity in assay validation

Abstract: a Linearity and linear range are the key evaluations of the accuracy in assay validation. The average deviation from linearity (ADL) and the sum of squares of deviations from linearity (SSDL) have been proposed for assessment of the linearity. However, both ADL and SSDL do no consider the variability of the assay for evaluation of linearity. Therefore, we proposed the coefficient of variation of deviations from linearity (CVDL) as an alternative measure for the linearity assessment. For the inference of evalua… Show more

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Cited by 10 publications
(5 citation statements)
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“…Under linearity in bivariate relationships and/or regression models, it is assumed that the dependent variable is a linear function of the independent variable (Niermann, 2007). Deviation from linearity is used to illustrate the significance (or lack thereof) of linearity of the respective sets of variables since it is one of the proposed parameters of assessing linearity (Liu, Chow, & Hsieh, 2009). The pertinent results are presented summarily in Table 3.…”
Section: Inferential Analysismentioning
confidence: 99%
“…Under linearity in bivariate relationships and/or regression models, it is assumed that the dependent variable is a linear function of the independent variable (Niermann, 2007). Deviation from linearity is used to illustrate the significance (or lack thereof) of linearity of the respective sets of variables since it is one of the proposed parameters of assessing linearity (Liu, Chow, & Hsieh, 2009). The pertinent results are presented summarily in Table 3.…”
Section: Inferential Analysismentioning
confidence: 99%
“…However, the sig linearity value < 0.05, which is 0.000 < 0.05, which means that linearity is very strong, meaning that the LINIER model is still able to explain variants well. Then the data on education level and legal compliance can be assumed to be linear (Liu et al, 2009). Based on the table above, it is known that the value of sig Deviation from linearity > 0.05, which is 0.052 > 0.05, which means that there is a linear relationship between legal culture variables (X3) and legal compliance (Y).…”
Section: B Linearity Testmentioning
confidence: 99%
“…Although it may seem that everything has been said on the subject of linearity, it is still an open question and subject to debate. It is therefore not surprising that some proposals are made from time to time to resolve this issue [54,[82][83][84][85][86][87][88][89][90][91][92].…”
Section: Ep6-a [79]mentioning
confidence: 99%
“…The stabilization of variance usually takes precedence over improving normality [160]. As stated by Acton [86] 'The gods who favour statisticians have frequently ordained that the world be…”
Section: Author Detailsmentioning
confidence: 99%