Abstract-Meeting the challenges of 5G demands better exploitation of the available spectrum by allowing multiple parties to share resources. For instance, a secondary unlicensed system can share resources with the cellular uplink of a primary licensed system for an improved spectral efficiency. This induces interference which has to be taken into account when designing such a system. A simple yet robust strategy is treating interference as noise (TIN), which is widely adapted in practice. It is thus important to study the capabilities and limitations of TIN in such scenarios. In this paper, we study this scenario modelled as multiple access channel (MAC) interfered by a Point-to-Point (P2P) channel, where we focus on the characterization of the rate region. We use improper Gaussian signaling (instead of proper) at the transmitters to increase the design flexibility, which offers the freedom of optimizing the transmit signal pseudo-variance in addition to its variance. We formulate the weighted maxmin problem as a semidefinite program, and use semidefinite relaxation (SDR) to obtain a near-optimal solution. Numerical optimizations show that, by improper Gaussian signaling the achievable rates can be improved upto three times when compared to proper Gaussian signaling.