Devil’s Claw (Harpagophytum procumbens): An Anti-Inflammatory Herb with Therapeutic Potential

Devil's Claw—A review of the ethnobotany, phytochemistry and biological activity of Harpagophytum procumbens

“…However, H. zeyheri has a lower concentration of the biologically active constituents. It is often included in raw materials and products as an adulterant of H. procumbens, the preferred species of commerce (McGregor et al, 2005). Harpagophytum procumbens is a commercially important plant species for the national income of Namibia for example, where it was an estimated h1.06 million in 2009 (Ridgway and Krugmann, 2011).…”

Analysis and stability of the constituents of Curcuma longa and Harpagophytum procumbens tinctures by HPLC-DAD and HPLC–ESI-MS

“…The pharmacologically active components of H. procumbens are considered to be the iridoid glycosides, other constituents, such as phenylethanoid glycosides and flavonoids are considered to contribute to the pharmacological action [10].…”

Estimation of the relative antiinflammatory efficacies of six commercial preparations of Harpagophytum procumbens (Devil's Claw)

“…formulations of H. procumbens have shown good profi les for the inhibition of infl ammatory responses, although intraperitoneal administration provided the best supportive evidence in various in vivo studies (McGregor et al, 2005). However, some negative or non-signifi cant results have also been obtained in in vitro studies that tested varied extracts for their action on leukotrienes and prostaglandins in human or mouse blood.…”