Diabetes and Sexuality

Kızılay, Fuat; Gali, Helena E.; Şerefoğlu, Ege Can

doi:10.1016/j.sxmr.2016.07.002

Cited by 77 publications

(57 citation statements)

References 69 publications

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“…ED can result in depression over a decreased sexual quality of life; however, depression and anxiety often precede ED and therefore this is not a simple linear relationship . ED is associated with a 2‐fold greater risk of CVD in men aged ≥55 years, and testosterone, which is often used to treat ED, may increase adverse cardiovascular events . DM is also associated with a 2‐fold increase in prevalence of CVD, and in a cohort of patients with DM, prevalence of ED was significantly greater in men with silent CAD, with a mean age of approximately 58 years .…”

Section: Discussionmentioning

confidence: 99%

“…9,11 ED is associated with a 2-fold greater risk of CVD in men aged ≥55 years, 21 and testosterone, which is often used to treat ED, may increase adverse cardiovascular events. 23 DM is also associated with a 2-fold increase in prevalence of CVD, 13,24 and in a cohort of patients with DM, prevalence of ED was significantly greater in men with silent CAD, with a mean age of approximately 58 years. 25 It has been hypothesised that ED and CVD are different manifestations of the same underlying systemic disorder in which chronic inflammation plays a role in atherosclerosis and flow-limiting stenosis.…”

Section: Ta B L E 4 Relationship Between Ed and Dmmentioning

confidence: 96%

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Real-world observational results from a database of 48 million men in the United States: Relationship of cardiovascular disease, diabetes mellitus and depression with age and erectile dysfunction

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Section: Ta B L E 4 Relationship Between Ed and Dmmentioning

confidence: 96%

Real-world observational results from a database of 48 million men in the United States: Relationship of cardiovascular disease, diabetes mellitus and depression with age and erectile dysfunction

et al. 2018

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“…[46][47][48] In addition to being intrinsic to vasculogenic ED, endothelial dysfunction is a central component of atherosclerotic disease and an important element in the pathological consequences of DM. 49 Middleaged men with ED are at an increased risk of not only having undiagnosed DM but also of developing it later in their lives, after the onset of ED. 9 Erectile dysfunction provides early warnings of CVD partly because of the narrowness of the arteries supplying blood to the penis.…”

Section: Erectile Dysfunction and Vascular Damagementioning

confidence: 99%

The pharmacist's role in improving the treatment of erectile dysfunction and its underlying causes

Taylor¹,

Giuliano

Hackett

et al. 2019

Research in Social and Administrative Pharmacy

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Erectile dysfunction (ED), which worldwide is likely to affect in excess of 300 million men by 2025, is often either untreated or insufficiently treated. It can be a prelude to other serious illnesses and may be a cause or consequence of depression in affected individuals. Among men younger than 60 years of age, ED can be a robust early-stage indicator of vascular disease and type 2 diabetes. Untreated or inadequately treated ED can also be a sign of poor communication between health professionals and service users of all ages. Improved treatment of ED could cost-effectively prevent premature deaths and avoidable morbidity. The extension of community pharmacy‒based health care would enable more men living with ED to safely access effective medications, along with appropriate diagnostic services and support for beneficial lifestyle changes such as smoking cessation in conveniently accessible settings. The task of introducing improved methods of affordably addressing problems linked to ED exemplifies the strategic challenges now facing health care systems globally. Promoting professionally supported self-care in pharmacies has the potential to meet the needs of aging populations in progressively more effective ways.

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“…A 2-DM fennállása esetén a libido csökken, az erektilis funkció és az ejakuláció romlik, valamint pszichés zavar és depresszió is kialakulhat. A szexuális funkcióra gyako-rolt hátrányos hatás elsősorban a metabolikus zavarnak, az idegkárosodásnak és az érrendszeri elváltozásoknak, valamint az alacsony tesztoszteronszintnek tudható be [21]. Maga a polineuropathia a hyperglykaemia, a metabolikus zavar és a microvascularis eltérések következménye.…”

Section: Diabetesunclassified

“…Férfiakban a leggyakoribb szexuális funkciózavar az ED. Az IR és a MS esetében a szabad tesztoszteronszint csökkenhet, és a hypogonadismus hozzájárul a férfi szexuális funkciózavarához [21]. Egy vizsgálat szerint a férfiak 16,1%-ában alacsony a tesztoszteronszint, 31,3%ában MS mutatható ki, továbbá 20%-a szenved ED-ben.…”

Section: Férfiakban Előforduló Szexuális Funkciózavarunclassified

A szexuális funkciózavar és a metabolikus szindróma kapcsolata

2019

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The prevalence of the metabolic syndrome, type 2 diabetes mellitus, cardiovascular diseases, obesity and depression have increased during the recent years. As the sexual dysfunction is also frequent, we aimed to search for the associations between sexual dysfunction and the metabolic syndrome and its components, respectively, by reviewing the literature. The clinical and biochemical components of the metabolic syndrome included cardiovascular disease, type 2 diabetes mellitus, visceral obesity and depression, furthermore, insulin resistance, atherogenic lipid profile, hypogonadism, chronic systemic inflammation and endothelial dysfunction were all demonstrated to affect adversely the sexual function. The dysfunction of the sexual arousal response shows a strong association in men and a milder one in women with the cardiovascular diseases and depression. Sexual function in diabetes mellitus is mostly impaired by microvascular injury, polyneuropathy and autonomic neuropathy. Erectile dysfunction and disorder of the female sexual arousal response and the orgasm, respectively, are associated with insulin resistance, atherogenic lipid profile and systemic inflammatory condition in overweight or obese patients. Sexual dysfunction particularly in men can be an early sign of the severe complications of metabolic syndrome. The pathogenetic link between the metabolic syndrome and the sexual dysfunction seems to be the insulin resistance. Both metabolic syndrome and sexual dysfunction can be restored by altering the lifestyle. Orv Hetil. 2019; 160(3): 98–103.

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Diabetes and Sexuality

Cited by 77 publications

References 69 publications

Real-world observational results from a database of 48 million men in the United States: Relationship of cardiovascular disease, diabetes mellitus and depression with age and erectile dysfunction

Real-world observational results from a database of 48 million men in the United States: Relationship of cardiovascular disease, diabetes mellitus and depression with age and erectile dysfunction

The pharmacist's role in improving the treatment of erectile dysfunction and its underlying causes

A szexuális funkciózavar és a metabolikus szindróma kapcsolata

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