Diabetes-associated cardiac autonomic neuropathy

Wooton, Angela K; Melchior, Lynne M.

doi:10.1097/01.npr.0000651104.30787.7a

Cited by 3 publications

(5 citation statements)

References 17 publications

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“…The present study is the first to evaluate the change in HRT, combined with HRV indices, after a long-term exercise program in DKD patients. Few studies have evaluated the diagnostic value of HRT on CAN in diabetic patients, although it has a significant diagnostic value so far [ 36 ]. HRT is considered an indicator of vagal activity and an independent factor of total mortality [ 37 ].…”

Section: Discussionmentioning

confidence: 99%

Effects of Home-Based Exercise Training on Cardiac Autonomic Neuropathy and Metabolic Profile in Diabetic Hemodialysis Patients

Michou

Liakopoulos

Roumeliotis

et al. 2023

Life

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Background: This study aimed to investigate the effects of a home-based exercise training program on Cardiac Autonomic Neuropathy (CAN) and metabolic profile in Diabetic Kidney Disease (DKD) patients undergoing maintenance hemodialysis (HD). Method: Twenty-eight DKD patients undergoing hemodialysis were randomly assigned into two groups. The exercise (EX) group followed a 6-month combined exercise training program at home, while the control (CO) group remained untrained. All participants at baseline and the end of the study underwent cardiopulmonary exercise testing (CPET), biochemical tests for glucose and lipid profile, and 24-h electrocardiographic monitoring for heart rate variability (HRV) analysis and heart rate turbulence (HRT). Results: At the end of the study, compared to the CO, the EX group showed a significant increase in serum high-density lipoprotein (HDL) by 27.7% (p = 0.01), peak oxygen uptake (VO2peak) by 9.3% (p < 0.05), the standard deviation of R-R intervals (SDNN) by 34.3% (p = 0.03), percentage of successive RR intervals higher than 50ms (pNN50) by 51.1% (p = 0.02), turbulence slope (TS) index by 18.4% (p = 0.01), and decrease in (glycated hemoglobin) HbA1c by 12.5% (p = 0.04) and low-frequency power LF (ms2) by 29.7% (p = 0.01). Linear regression analysis after training showed that VO2peak was correlated with SDNN (r = 0.55, p = 0.03) and HF (r = 0.72, p = 0.02). Multiple regression analysis indicated that the improvement of sympathovagal balance and aerobic capacity depended on patients’ participation in exercise training. Conclusion: In conclusion, a 6-month home-based mixed-type exercise program can improve cardiac autonomic function and metabolic profile in DKD patients on HD.

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Section: Discussionmentioning

confidence: 99%

Effects of Home-Based Exercise Training on Cardiac Autonomic Neuropathy and Metabolic Profile in Diabetic Hemodialysis Patients

Michou

Liakopoulos

Roumeliotis

et al. 2023

Life

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“…Kardiyovasküler sistemin parasempatik ve sempatik fonksiyonunu değerlendirmede en yaygın kullanılan testler ile tanı konulur. Bu testler ayakta kalmaya kalp atış hızı cevabı, zorlu solunuma kalp hızı cevabı, valsalva manevrasına kalp hızı cevabı, ayakta kalmaya sistolik kan basıncı cevabı, izometrik egzersize diyastolik kan basıncı cevabı, 24 saatlik holter takibidir (10). Gastrointestinel sistemde özofagial disfonksiyon, gastroparezi, diyare ve konstipasyona neden olur.…”

Section: Diyabetik Nöropati Patofizyolojisiunclassified

“…Tüm sağlık profesyonelleri tarafından tarama testlerini kolaylıkla uygulayabilmesi erken tanılamayı kolaylaştıracaktır. Diyabetik nöropati tanısında gerekli görülmesi durumunda elektrofizyolojik inceleme (Elektromiyelografi), basit tarama testleri (Semmes-Weinstein monoflaman testi), biyopsi (sinir, deri ), kantitatif duyu testleri (sıcak, soğuk ve vibrasyon eşiği ölçümü), korneal konfokal mikroskopik inceleme (10) ve kardiyak otonom nöropati için tanısal testler (16). (valsalva manevrasına kalp hızı yanıtı, derin nefes esnasında kalp hızı değişikliği, ayağa kalkıldığında ani kalp hızı tepkisi, ayağa kalkışta kan basıncı yanıtı, el yumruğu sıkıldığında kan basıncı yanıtı) yapılmaktadır.…”

Section: Diyabetik Nöropati Patofizyolojisiunclassified

Diyabetik Nöropatinin Yönetiminde Güncel Tedavi Yaklaşımları ve Hemşirelik Bakımı

GÖRGÜLÜ¹,

ÇİFTÇİ

Polat

2022

Sağlık Bilimlerinde Değer

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Diabetic neuropathy is one of the most common neurological complications of diabetes with a high risk of morbidity that affects the quality of life of individuals. Many people with diabetes do not report symptoms or problems associated with diabetic neuropathy. All patients with diabetes should be screened annually for neuropathy with a neuropathy-specific history, screening test, and physical examination. These individuals are at high risk for poor quality of life, neuropathic pain, falls, development of foot ulcers and infections, and amputation. In order to minimize complications and improve quality of life, early diagnosis of individuals with diabetic neuropathy, evaluation with valid and reliable screening tools, and management of diabetic neuropathy are important. Management of diabetic neuropathy requires a multidisciplinary team approach. Nurses, who are an important member of this team, are among the responsibilities of nurses to raise awareness of individuals with diabetic neuropathy and those at risk of developing neuropathy, to plan interventions for high-risk groups, and to ensure that they gain correct knowledge and behavior. The nurse's awareness and knowledge about the screening, diagnosis, treatment and care practices of individuals with diabetic neuropathy will be beneficial in preventing or reducing the development of negative outcomes. Keywords: Diabetic neuropathy; scanning; treatment; care; nursing.

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“…Diabetes is the most common endocrine disease often accompanied by complications such as periodontitis, kidney failure, blindness, etc. 1–4 So far, no definite cure has been developed, and continuous monitoring of blood glucose is needed to help doctors guide patients' treatment plans. The diagnostic methods for blood glucose detection are predominantly based on analyzing finger blood, venous blood, and intercellular fluid, which are all invasive.…”

Section: Introductionmentioning

confidence: 99%

“…The diagnostic methods for blood glucose detection are predominantly based on analyzing finger blood, venous blood, and intercellular fluid, which are all invasive. 5 Over the last decade, scientists have been trying to develop non-invasive methods for detecting glucose in sweat, 6 tears, 7 urine, 8 or saliva. 9,10 Among these specimens, saliva is an attractive alternative to blood, as its collection is inexpensive, and the method is completely non-invasive.…”

Section: Introductionmentioning

confidence: 99%

Low-fouling CNT-PEG-hydrogel coated quartz crystal microbalance sensor for saliva glucose detection

et al. 2021

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Diabetes-associated cardiac autonomic neuropathy

Abstract: Here are a few key statistics about heart disease, stroke, other cardiovascular diseases and their risk factors, in addition to commonly

Cited by 3 publications

References 17 publications

Effects of Home-Based Exercise Training on Cardiac Autonomic Neuropathy and Metabolic Profile in Diabetic Hemodialysis Patients

Effects of Home-Based Exercise Training on Cardiac Autonomic Neuropathy and Metabolic Profile in Diabetic Hemodialysis Patients

Diyabetik Nöropatinin Yönetiminde Güncel Tedavi Yaklaşımları ve Hemşirelik Bakımı

Low-fouling CNT-PEG-hydrogel coated quartz crystal microbalance sensor for saliva glucose detection

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