Diabetes in South and Central America: An update

Aschner, Pablo; Aguilar-Salinas, Carlos A.; Aguirre, Loreto; Franco, Laércio Joel; Gagliardino, Juan José; Lapertosa, Silvia; Seclén, Segundo; Vinocour, Mary

doi:10.1016/j.diabres.2013.11.010

Cited by 91 publications

(79 citation statements)

References 19 publications

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“…In the South and Central America region, 24% of adults with diabetes are undiagnosed, extending to 50% in some countries [2]. Diabetes was the fifth leading cause of death in Venezuela in 2012 [3].…”

Section: Introductionmentioning

confidence: 99%

FINDRISC Modified for Latin America as a Screening Tool for Persons with Impaired Glucose Metabolism in Ciudad Bolívar, Venezuela

et al. 2019

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Objective: The Finnish Diabetes Risk Score (FINDRISC) includes anthropometric, metabolic, and lifestyle factors that predict type 2 diabetes mellitus. The objective of this study was to evaluate the FINDRISC modified for Latin America (LA-FINDRISC) as a screening tool for persons with impaired glucose metabolism in Ciudad Bolívar, Venezuela. Methods: Subjects aged between 18 and 70 years of both sexes without known diabetes were invited to participate. After informed consent, they were screened with the LA-FINDRISC questionnaire and then given an oral glucose tolerance test, using the American Diabetes Association criteria for diagnosis. To obtain the cutoff point of LA-FINDRISC for predicting impaired glucose regulation, a receiver operating characteristic curve was constructed. Results: A total of 200 subjects were evaluated, 64.5% female, with a mean age of 35.20 ± 13.84 years. Of these, 158 (79%) did not present with carbohydrate metabolism disorder, while 42 (21%) did. Age (p = 0.0001), body mass index (p = 0.011), and waist circumference (p = 0.031) were significantly higher in subjects with impaired glucose regulation when compared to those without it. There were a significantly greater number of sedentary (p = 0.039) and hypertensive subjects (p = 0.0001), as well as those with a history of glucose >100 mg/dL (p = 0.0001), in the impaired glucose metabolism group. A cutoff LA-FINDRISC of 14 points predicted a high risk of impaired glucose regulation with a sensitivity of 45.2% and a specificity of 89.9%. Conclusion: A LA-FINDRISC >14 points had low sensitivity but high specificity for predicting carbohydrate metabolism disorders in this group of patients from Ciudad Bolívar.

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Section: Introductionmentioning

confidence: 99%

FINDRISC Modified for Latin America as a Screening Tool for Persons with Impaired Glucose Metabolism in Ciudad Bolívar, Venezuela

et al. 2019

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“…Según los reportes sobre la proporción de los casos de TB+DM2, en los Estados Unidos de América es 11,4% (7) , 13,1% en Japón (8) , 29,6% en México (9) y en el Perú es 6,3% (10) . Si bien la prevalencia de diabetes en Perú es baja, su incremento en los próximos años podría ocasionar el incremento de la comorbilidad TB+DM2 (11,12) .…”

Section: Introductionunclassified

Características del diagnóstico y tratamiento de la tuberculosis pulmonar en pacientes con y sin diabetes mellitus tipo 2

Carrión-Torres

Cazorla-Saravia

Sales

et al. 2015

Rev Peru Med Exp Salud Publica

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Objetivos. Conocer si existen diferencias en las características demográficas, clínicas y radiológicas entre los pacientes con tuberculosis pulmonar (TB) y pacientes con TB y diabetes mellitus tipo 2 (TB+DM2). Materiales y métodos. Estudio observacional de cohorte retrospectiva. Se compararon las características clínicas de los pacientes según el sexo, la edad, el tiempo de negativización del esputo, la presencia de cavitación así como la tasa de curación, duración del tratamiento y la proporción del cambio en el esquema del tratamiento antituberculoso en pacientes con y sin DM2 atendidos por el Programa de Control de Tuberculosis entre 2010 y 2012 en la Red Asistencial Rebagliati de Lima, Perú. Resultados. Se incluyeron 31 pacientes con TB+DM2 y 144 pacientes con TB. Se encontraron diferencias (p<0,05) en el método de diagnóstico, el promedio de síntomas y en el patrón de resistencia de TB entre los pacientes con y sin DM2. La presencia de cavitación fue más frecuente en los pacientes con TB+DM2; ser paciente de TB+DM2 retraso la negativización del BK de esputo (RRa 4,16; IC 95 %: 1,1-1,6) en el análisis de regresión de Cox ajustado. Conclusiones. Existen diferencias en las características demográficas, clínicas y radiológicas en los pacientes con tuberculosis con y sin DM2. El periodo de negativización del esputo es mayor en los pacientes con DM2. Palabras clave: Tuberculosis; Diabetes mellitus tipo 2; Estudios longitudinales; Comorbilidad; (fuente: DECS BIREME). CHARACTERISTICS OF THE DIAGNOSIS AND TREATMENT OF PULMONARY TUBERCULOSIS IN PATIENTS WITH AND WITHOUT DIABETES MELLITUS TYPE 2 ABSTRACTObjectives. To determine whether there are demographic, clinical and radiological differences among patients with pulmonary tuberculosis (TB) and patients with TB and type 2 diabetes mellitus (DM2 + TB). Materials and methods. Observational retrospective cohort study. We compared the clinical characteristics of patients according to sex, age, time to sputum conversion to negative, presence of cavitation and the cure rate, duration of treatment and the proportion of change of treatment regimen, in patients with and without DM2 served by the Tuberculosis Control Program from 2010 to 2012 in the Rebagliati Healthcare Network of Lima, Peru. Results. 31 patients with TB+DM2 and 144 patients with TB were included. Differences (p<0.05) in the diagnostic method, the average of symptoms and the resistance pattern of TB among patients with and without DM2 were found. The presence of cavitation was more frequent in patients with TB + DM2. Having TB + DM2 delayed the time to sputum smear conversion to negative (RRa 4.16, 95% CI: 1.1-1.6) in the adjusted Cox regression analysis. Conclusions. There are differences in demographic, clinical and radiological characteristics in TB patients with and without DM2.The time to sputum conversion to negative is greater in patients with DM2.

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“…Así, en América Latina se han encontrado cifras muy altas, hasta de un 70% de pacientes diabéticos con control metabólico inadecuado (16)(17)(18)(19). En nuestro país hay reportes que cifran el control metabólico adecuado en 50% de pacientes diabéticos, tomando en cuenta sólo glucosa y hemoglobina glicosilada (HbA1C) (20).…”

Section: Introductionunclassified