Diabetes increases the risk of COVID-19 in an altitude dependent manner: An analysis of 1,280,806 Mexican patients

León-Abarca, Juan Alonso; Portmann-Baracco, Arianna; Bryce-Alberti, Mayte; Ruiz-Sánchez, Carlos; Accinelli, Roberto A.; Soliz, Jorge; Gonzáles, Gustavo F.

doi:10.1371/journal.pone.0255144

Cited by 31 publications

(25 citation statements)

References 68 publications

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“…It has been reported that the prognosis is worse in patients with type 2 DM who have metabolic syndrome (MetS) components at the onset of the COVID-19 infection. 16 …”

Section: Discussionmentioning

confidence: 99%

COVID-19 Pneumonia in Patients with Impaired Fasting Glucose, Newly Diagnosed Diabetes and Pre-Existing Diabetes: A Tertiary Center Experience

Böyük

Akın²,

Aladağ³

et al. 2022

Journal of Investigative Medicine

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COVID-19 infection is known to increase mortality in patients with diabetes. We aim to demonstrate the differences in disease course and clinical outcomes of patients with COVID-19 regarding the presence of impaired fasting glucose, pre-existing diabetes mellitus (DM) or new-onset DM. 236 patients with positive reverse transcription-PCR tests for SARS-CoV-2 were included in this single-center, retrospective observational study between March 2020 and May 2021. Laboratory results, comorbidities, medications and imaging findings were noted. Logistic regression was used to estimate associated factors for admission to the intensive care unit (ICU). 43 patients with normal glucose, 53 with impaired fasting glucose, 60 with newly diagnosed DM, and 80 with pre-existing DM were classified. Patients with pre-existing DM had higher fasting glucose and glycated hemoglobin than the other groups (p<0.001 for all). Patients with newly diagnosed DM were more likely to need dexamethasone 6 mg (p=0.001). In both newly diagnosed diabetes and impaired fasting glucose groups, 250 mg methylprednisolone was needed at higher rates (p=0.002). Newly diagnosed DM had higher rates of intubation (21.6%) and more mortality (20.0%) (p=0.045 and p=0.028, respectively). Mortality and hospitalization in the ICU were lower in the group receiving antidiabetic treatment. The risk of ICU attendance was higher in patients with impaired fasting glucose (HR=1.71, 95% CI: 0.48 to 6.08) and newly diagnosed DM (HR=1.88, 95% CI: 0.57 to 6.17), compared with pre-existing DM and non-diabetics. Newly diagnosed DM and impaired fasting glucose are associated with increased mortality and intubation in inpatients with COVID-19.

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“…It has been reported that the prognosis is worse in patients with type 2 DM who have metabolic syndrome (MetS) components at the onset of the COVID-19 infection. 16 …”

Section: Discussionmentioning

confidence: 99%

COVID-19 Pneumonia in Patients with Impaired Fasting Glucose, Newly Diagnosed Diabetes and Pre-Existing Diabetes: A Tertiary Center Experience

Böyük

Akın²,

Aladağ³

et al. 2022

Journal of Investigative Medicine

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“…The presence of DM was identified in 12.97% of the total number of records. According to the findings, diabetes patients were more likely to contract COVID-19 and develop pneumonia [57] . Liu Z et al carried out a retrospective observational study for a large sample group (1880 patients).…”

Section: What Effect Does Diabetes Mellitus Have On Covid-19 and Vice...mentioning

confidence: 97%

COVID-19 and diabetes: Association intensify risk factors for morbidity and mortality

Sharma

Behl

Sharma

et al. 2022

Biomedicine & Pharmacotherapy

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“…COVID-19 and diabetes mellitus are correlated in a bidirectional manner, according to research[ 26 ]. Diabetes mellitus is a common comorbidity among COVID-19 patients[ 27 ]. Diabetes exacerbates disease severity and mortality, increasing the probability of infection with SARS-CoV-2[ 28 ].…”

Section: Discussionmentioning

confidence: 99%

Assisting individuals with diabetes in the COVID-19 pandemic period: Examining the role of religious factors and faith communities

Eseadi¹,

Ossai²,

Onyishi³

et al. 2022

WJCC

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With the onset of the coronavirus disease 2019 (COVID-19) pandemic, diabetes management has become more challenging than it has ever been. Studies on the management of diabetes during this time are required. Unfortunately, the lack of information on the potential role of religious factors and faith communities in diabetes management during the COVID-19 era prevents us from fully understanding the issue of diabetes management during the COVID-19 pandemic period. People with chronic conditions such as diabetes may benefit from some form of religious support from faith communities and their ability to cope could be fostered by some religious factors. It is unclear how religious factors and faith communities contribute to diabetes management. In this article, the authors examine how people with diabetes can be aided in the COVID-19 pandemic period from the perspective of religious factors and faith communities. Based on the studies identified, it appears that religious factors and faith communities play an important role in managing diabetes among patients during the COVID-19 pandemic.

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Diabetes increases the risk of COVID-19 in an altitude dependent manner: An analysis of 1,280,806 Mexican patients

Cited by 31 publications

References 68 publications

COVID-19 Pneumonia in Patients with Impaired Fasting Glucose, Newly Diagnosed Diabetes and Pre-Existing Diabetes: A Tertiary Center Experience

COVID-19 Pneumonia in Patients with Impaired Fasting Glucose, Newly Diagnosed Diabetes and Pre-Existing Diabetes: A Tertiary Center Experience

COVID-19 and diabetes: Association intensify risk factors for morbidity and mortality

Assisting individuals with diabetes in the COVID-19 pandemic period: Examining the role of religious factors and faith communities

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