Diabetes prevalence and its impact on health‐related quality of life in tuberculosis patients

Abstract

Addressing screening measures and glycaemic control along with social determinants such as literacy level and alcohol consumption could be an important means of improving the HRQoL of TB with DM patients.

Effects of comorbidities on quality of life in Filipino people with tuberculosis

“…18 Another study in India (using the TB-specific Dhingra & Rajpal DR-12 scale), reported decreased scores in the socio-psychological and exercise adaptation domains in persons with DM aged over 50 years; while uncontrolled versus controlled DM was associated with lower scores, but only at the end of TB treatment. 5 Despite a high prevalence of severe undernutrition (23% BMI , 15 kg/m 2 ), a possible effect of this important comorbidity was not reported. 5 Within our sub-set of participants with known HIV status, living with HIV infection initially appeared to be associated with increased QoL domain scores, but after adjustment, this association trended towards decreased scores, likely due to confounding by age and education, which were higher in those with HIV and also positively associated with QoL domain scores, Thus, compared to other studies in Ethiopia the impact of comorbid HIV appeared to be limited.…”

“…5 Despite a high prevalence of severe undernutrition (23% BMI , 15 kg/m 2 ), a possible effect of this important comorbidity was not reported. 5 Within our sub-set of participants with known HIV status, living with HIV infection initially appeared to be associated with increased QoL domain scores, but after adjustment, this association trended towards decreased scores, likely due to confounding by age and education, which were higher in those with HIV and also positively associated with QoL domain scores, Thus, compared to other studies in Ethiopia the impact of comorbid HIV appeared to be limited. 19,20 As the majority of those living with HIV were already in care at the same site as their TB treatment and receiving antiretroviral therapy, this suggests that in the context of adequate care, the additional impact of comorbid HIV in TB is not necessarily great.…”

“…3,4 Few studies in people with active TB disease have included an assessment of the impact of comorbidities on HrQoL, although a recent prospective cohort study in India reported a negative effect of DM using the TB-specific Dhingra and Rajpal (DR-12) scale. 5 Although the Philippines has a high TB burden, there are currently limited HrQoL data from the Philippines or on comorbidities in TB. Within a cross-sectional study of Filipino people with active TB disease enrolled in TB-DOTS clinics (ISRCTN12506117), we investi-gated, as a primary objective, the prevalence of DM and moderate/severe acute undernutrition and factors associated with these comorbidities, reported elsewhere.…”

Calidad de vida relacionada con la salud de pacientes con tuberculosis pulmonar

“…25 Resultados similares se encontraron en un estudio prospectivo realizado en India, donde la CVRS fue peor en individuos con diabetes y TB, especialmente en los sujetos con glucemia no controlada, en comparación con sujetos sin diabetes. 28 Un estudio prospectivo en México encontró que pacientes con diabetes y TB tienen mani-festaciones clínicas más graves, retraso en negativización de baciloscopia y una mayor probabilidad de fracaso del tratamiento, recurrencia y recaída, lo que podría afectar negativamente la CVRS de los pacientes. 29 Adicionalmente, existe evidencia de que pacientes con el binomio TB/VIH presentan una peor CVRS que sujetos sin su presencia.…”

Normal Fasting Blood Sugar Levels and Medication Adherence Improve the Quality of Life of Type 2 Diabetes Mellitus Patients in Primary Health Facilities

“…Many factors can be attributed to the QOL of DM patients. Research in Singapore and Malaysia shows that distress, poor sleep quality, and comorbidity are associated with a decrease in DM patients' HRQOL [6,[27][28][29]. It has been proven that controlled blood sugar levels © 2018 The Authors.…”