Diabetic Glomerulosclerosis in a Patient With Chronic Pancreatitis

The Prevalence and Severity of Microvascular Complications in Pancreatic Diabetes and IDDM

“…Additionally, in another report, 7% had overt nephropathy (urinary protein excretion >500 /u-g), and 17% renal insufficiency (serum creatinine >133 /xmol/1) (12). The typical clinical diagnosis of diabetic nephropathy was not confirmed histologically in these studies, but autopsy findings of diabetic glomerulosclerosis have been described in isolated cases of PD (13). These data suggest that all forms of renal dysfunction and retinopathy may occur in PD.…”

Effet protecteur de l'h�mochromatose vis-�-vis des l�sions vasculaires s�niles ou diab�tiques

“…Cette protection n'est pus totale comme le montrent los rares eas publi6s de r6tinopathie typique [7,23,32,42,69,73,85] et de ndphroputhie de Kimmelstiel-Wilson [7,44]. Si rare soient-fls, ces cas constituent un puissant argument en faveur de la th~se qui fair des complications vasculaires une cons6quence ((6vituble~) du dds6quflibre m6tabolique qu'est le diabSte, et co, quelle que soit la cause de ce diab~te chez l'homme: pancr6atectomie totale [13,27,30], puncrdatite chronique [23,26,28,44,79,85], acrom6galie [54], ph@ochromocytome [25], maladie de Cushing [54] ou traitement prolong6 aux corticoides [83] et chez divers animaux rendus artificiellement diub6tiques sans y ~tre gdn6tiquement pr@dispos6 [6,9,29,34,37,45,50,55,56,59,61,63,64,65,75,84].…”