Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland

Lewis, Aaron; Tong, Teresa; Maghami, Ellie

doi:10.1016/j.otc.2015.11.001

Cited by 152 publications

(185 citation statements)

References 117 publications

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“…Metastases in regional lymph nodes and lungs have been described as common (Uzal et al, 2016); however, in this case, pulmonary infiltration was observed. Microscopically, the neoplasm of the present description showed epithelial cells arranged in clusters, sometimes forming lobes, suggesting a structural glandular pattern (Lewis et al, 2016). The cell morphology was variable, but predominantly rounded, with abundant eosinophilic cytoplasm.…”

Section: Discussionmentioning

confidence: 52%

Parotid gland adenocarcinoma in a cow: case report

Queiroz

Magalhães

et al. 2018

Arq. Bras. Med. Vet. Zootec.

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A 9-year-old Girolando dairy cow, weighing 400kg, with a history of increased volume in the right parotid region, which extended to the submandibular region, was assisted. Fine needle aspiration cytology was performed, and the cytological findings were consistent with malignant neoplasm of epithelial origin (carcinoma). Because of the unfavorable prognosis, the animal was euthanized and submitted to an anatomopathological examination. Samples of the increased parotid and affected lymph nodes were collected for histopathological evaluation. The microscopic changes were accentuated features of anaplasia, moderate cell proliferation, atypical mitotic figures, and necrosis. Stroma ranged from delicate to scirrhous, and the tumor boundaries were not distinct. These findings substantiated the preliminary histomorphological diagnosis of undifferentiated carcinoma with metastasis in lymph nodes. Immunohistochemical tests were performed with anti-CK Pan (clone AE1AE3), anti-CK HMW (clone 34βE12), anti-CK19 (clone RCK108), anti-vimentin (clone V9), anti-S100 (polyclonal), and antiandrogen (polyclonal) antibodies. The immunophenotype favored the diagnosis of salivary gland adenocarcinoma. Despite the rareness in cattle, salivary gland adenocarcinoma should be considered in the differential diagnosis of diseases that occur with increased volume in the head, lymphadenopathy, drooling, dysphagia, and progressive weight loss.

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Section: Discussionmentioning

confidence: 52%

Parotid gland adenocarcinoma in a cow: case report

Queiroz

Magalhães

et al. 2018

Arq. Bras. Med. Vet. Zootec.

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“…MEC is the most common salivary cancer affecting the parotid gland and comprising approximately 30% of malignant tumors [2]. It usually affects patients from third to ifth decade of life with slight female preponderance [4].…”

Section: Discussionmentioning

confidence: 99%

“…Although MEC accounts for less than 10% of all tumors of the salivary gland, it constitutes approximately 30% of all malignant tumors of the salivary gland [2]. MEC is the most common malignant tumour to arise in children and adolescents under 20 years of age [3].…”

Section: Introductionmentioning

confidence: 99%

“…Pain and facial paralysis are associated with high grade malignant tumors. They can recur, and they can metastasize to regional lymph nodes or distant viscera [2,3]. Because of the relative rarity of these tumors and the remarkable variability in their biological behaviour, opinions differ about the appropriate classi ication, grading, and treatment [4].…”

Section: Introductionmentioning

confidence: 99%

“…Because of the relative rarity of these tumors and the remarkable variability in their biological behaviour, opinions differ about the appropriate classi ication, grading, and treatment [4]. Although surgery generally is accepted as the primary treatment for MEC, the extent of parotidectomy, the indications for neck dissection and need for adjuvant therapy are not clear [2,4].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Recurrent Mucoepidermoid Carcinoma of Parotid with Facial Tics - Report of an unusual case

Sakthivel¹

2017

Heighpubs Otolaryngol and Rhinol

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We report an interesting case of a 21 year old male who presented with recurrent mucoepidermoid carcinoma of parotid with facial nerve involvement as facial tics. Intraoperatively, the tumour was noted to be fi rm, irregular and adherent to the underlying structures. The patient underwent extended total parotidectomy, division of buccal branch of facial nerve, selective neck dissection with cervical local rotational fl ap repair and post-operative radiotherapy. This presentation of Mucoepidermoid carcinoma with involvement of facial nerve as facial tics is one of the rare unique reported cases.

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Salivary

Eskander¹

2022

Essential Cases in Head and Neck Oncology

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Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland

Cited by 152 publications

References 117 publications

Parotid gland adenocarcinoma in a cow: case report

Parotid gland adenocarcinoma in a cow: case report

Recurrent Mucoepidermoid Carcinoma of Parotid with Facial Tics - Report of an unusual case

Salivary

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