Diagnosis and treatment of acute coronary syndrome during the novel coronavirus infection COVID-19 pandemic

Намитоков, А. М.; Ishevskaya, O.P.; Fetisova, V. I.; Космачева, Е. Д.; Pоrkhanov, V. A.

doi:10.15829/1560-4071-2020-3854

Cited by 6 publications

(4 citation statements)

References 51 publications

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“…Relationships and Activities: none. 1 Meshalkin National Medical Research Center, Novosibirsk; 2 В настоящее время одной из ведущих проблем мирового здравоохранения является пандемия новой коронавирусной инфекции (COVID-19), вызванной коронавирусом SARS-CoV-2 [1]. Ишемическая болезнь сердца (ИБС) занимает важную роль в пандемии COVID-19, т.к.…”

Section: Discussionunclassified

“…Ишемическая болезнь сердца (ИБС) занимает важную роль в пандемии COVID-19, т.к. вне зависимости от эпидемиологической обстановки была и остается ведущим фактором риска (ФР) возникновения острых состояний и летального исхода [2].…”

Section: Discussionunclassified

“…Развитие острого коронарного синдрома (ОКС) у больных ИБС в условиях пандемии COVID-19 требует разработки оптимальной маршрутизации с целью оказания экстренной хирургической помощи при неэффективности консервативной терапии и определения дальнейшей тактики ведения данных пациентов. Многообразие клинических проявлений COVID-19, а также сложности с ранней диагностикой усложняют данную задачу [2]. Помимо этого, ИБС и ее ФР -сахарный диабет (СД), ожирение, хроническая обструктивная болезнь легких обусловливают тяжелое течение COVID-19 [3].…”

Section: Discussionunclassified

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Myocardial revascularization in patients with acute coronary syndrome in the context of COVID-19 pandemic: a single-center prospective cohort study

et al. 2021

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Aim. To assess the outcomes of myocardial revascularization (MR) and identify risk factors for early postoperative complications in patients with coronary artery disease (CAD) with acute coronary syndrome (ACS) in the context of coronavirus disease 2019 (COVID-19) pandemic.Material and methods. The study included 769 patients aged 67,0±4,4 years with CAD with ACS in the period from April to October 2020. In an expedited manner, percutaneous transluminal coronary angioplasty (n=699) and on pump coronary artery bypass grafting (CABG) (n=70) were performed. All patients underwent a COVID-19 rapid tests. After MR, the following outcomes were recorded: adverse cardiovascular events and other complications; various surgical interventions; bilateral COVID-19 pneumonia; death. The follow-up period lasted 30 days.Results. During the hospitalization, COVID-19 was detected in 5,3% of patients (n=41). Among them, bilateral multisegmental pneumonia developed in 48,8%. Among infected patients, COVID-19-related mortality in the early postoperative period was 9,8%. The all-cause mortality rate was 0,7%. On pump CABG significantly increases the risk of developing COVID-19 pneumonia (odds ratio (OR), 23,2; 95% confidence interval (CI) 14,2-35,4; p<0,001). After MR, COVID-19 pneumonia was associated with respiratory (OR, 7,6; 95% CI, 4,3-11,5; p=0,001) and heart failure (OR, 4,2; 95% CI, 2,9-8,6; p=0,001), atrial fibrillation (OR, 8,3; 95% CI, 4,1-13,9; p=0,001), as well as with all-cause mortality (OR, 10,3; 95% CI, 5,2-16,7; p=0,005). Recurrent transmural myocardial infarction in patients with CAD was associated with heart failure after MR (OR, 7,1; 95% CI, 2,4-12,6; p=0,012).Conclusion. Conducting on pump CABG in patients with CAD with ACS is the leading trigger for developing COVID-19 pneumonia, which, during hospitalization after MR, was associated not only with respiratory complications, but also with impaired heart function, which significantly increases the death risk in this category of patients.

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Section: Discussionunclassified

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Myocardial revascularization in patients with acute coronary syndrome in the context of COVID-19 pandemic: a single-center prospective cohort study

et al. 2021

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“…Популяционные закономерности, полученные для мужчин и женщин среднего возраста, также определяют особенности подхода при планировании профилактических мероприятий в этой возрастной категории. В условиях цивилизации современного мира, которую еще более усугубили реалии пандемии новой коронавирусной инфекции, снижение ФА стало одной из важнейших черт, повышающей риск общей и сердечно-сосудистой смерти [5,15]. При положительной тенденции к росту активного досуга среди мужчин среднего возраста имеет место снижение ФА и трудоспособности за последний год, несмотря на попытки к регулярным физическим упражнениям, значительно превышающие такое стремление у мужчин молодого возраста.…”

Section: материал и методыunclassified

Age-related trends of physical activity and work capacity among men and women in an open urban population

Акимов

2021

Russ J Cardiol

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Aim. To establish parameters of physical activity (PA) and work capacity among men and women in an open population of Western Siberia city, depending on age.Material and methods. Cross-sectional epidemiological studies were carried out among open male and female population of a middle-urbanized city of Western Siberia (Tyumen). Representative samples of 1000 people aged 25-64 years (250 people in each life decade) were analyzed. PA and work capacity were determined according to the WHO MONICA-psychosocial questionnaire “Awareness and Attitude towards Health”.Results. Age-related trends among young men of middle urbanized Western Siberia city were manifested by PA increase during the last year (in 25-34 yearage group — in 20,9%, in the general population — in 13,8% (p=0,0205)). During the last year, a decrease and an increase in work capacity was revealed in young women (33,6%) and young men (17,5%), respectively. Age-related trends among middle-aged people of both sexes were manifested by low self-esteem — in men by the sixth decade of life (0,6% vs 8,9%, p=0,0002), in women — by the fifth decade of life (3,4% vs 8,2%, p=0,0442). In men, with a decrease in PA and work capacity during the last year, an increase in outdoor activities was revealed (15,8% vs 27,7%, p=0,0020).Conclusion. Since the promotion of physical literacy should be among the state priorities, the presented data can serve as the basis for planning populationbased preventive measures, intended for working-age men and women in middleurbanized Siberian cities.

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Single-center register of myocardial revascularization in patients with coronary artery disease and acute coronary syndrome in the context of COVID-19 pandemic

Kamenskaya

Клинкова

Логинова

et al. 2021

Cardiovasc Ther Prev

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Aim. To assess the short- and long-term outcomes of myocardial re- vascularization (MR) in patients with coronary artery disease (CAD) and acute coronary syndrome (ACS) in the context of coronavirus disease 2019 (COVID-19) pandemic.Material and methods. In the period from April to August 2020, 550 patients with CAD and ACS were included in the register. Emergency percutaneous transluminal coronary angioplasty (n=499) and on-pump coronary artery bypass grafting (CABG) (n=51) were performed. The follow-up period lasted 6 months. The pattern of complications after MR and effects of COVID-19 were analyzed.Results. The studied cohort is represented by patients with CAD >65 years old. ST segment elevation ACS was detected in 23%, acute myocardial infarction — in 59,1%, in other cases — unstable angina. During hospitalization after MR, atrial fibrillation prevailed among cardiovascular complications (4,7%). During this period, 29 (5,3%) patients was diagnosed with COVID-19. In the short-term period after MR, 3 (0,5%) people died due to COVID-19 complications-. In the long-term period after MR, 4 (0,7%) cases of non-fatal stroke were registered, while repeated MR — in 7,1%. The all-cause mortality rate was 1,3% (n=7), of which 57,1% of patients died due to COVID-19 complications. In the subgroup of patients who underwent CABG, the greatest number of in-hospital complications was noted, where exudative pleurisy, atrial fibrillation and anemia prevailed. Of the patients with COVID-19, pneumonia in the short-and long-term posto perative periods was recorded in 48,3 and 61,3%, respectively. Pneumonia is associated with respiratory failure, cardiac dysfunction, and anemia. The risk of COVID-19 pneumonia during the entire follow-up period was higher in patients with ACS who underwent CABG (odds ratio, 19,4; confidence interval: 13,3-26,1; p<0,001). The overall survival rate was 98,7%.Conclusion. COVID-19 infection in patients with ACS after MR effects pattern of postoperative complications. The proportion of COVID-19 pneumonia in patients with ACS in hospital, short- and long-term postoperative periods after MR significantly exceeds that in the general population. The leading factor associated with COVID-19 pneumonia in patients with ACS is on-pump CABG.

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Diagnosis and treatment of acute coronary syndrome during the novel coronavirus infection COVID-19 pandemic

Cited by 6 publications

References 51 publications

Myocardial revascularization in patients with acute coronary syndrome in the context of COVID-19 pandemic: a single-center prospective cohort study

Myocardial revascularization in patients with acute coronary syndrome in the context of COVID-19 pandemic: a single-center prospective cohort study

Age-related trends of physical activity and work capacity among men and women in an open urban population

Single-center register of myocardial revascularization in patients with coronary artery disease and acute coronary syndrome in the context of COVID-19 pandemic

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