Diagnosis and treatment of coenurosis in sheep

Scott, Phil

doi:10.1016/j.vetpar.2012.03.034

Cited by 39 publications

(53 citation statements)

References 12 publications

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“…Neurological signs were observed between 120 and 240 days from the first clinical examination. As has been previously reported, the deterioration of the clinical condition seems to change more rapidly when the cyst is localized in the caudal fossa [14,26]. Given that the growing cyst can determine bone adaptive morphological modification, it is likely that these changes are less effective when the cyst is located in the caudal fossa [12].…”

mentioning

confidence: 61%

Clinical evolution of cerebral coenurosis from invasive to chronic infection in sheep and a goat

Evangelisti

Varcasia

Deiana

et al. 2016

J Infect Dev Ctries

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This survey describes the evolution in vivo of Coenurus cerebralis in small ruminants. At presentation, neurological signs and cerebrospinal fluid (CSF) features were suggestive of multifocal or diffuse inflammatory reaction. Magnetic resonance imaging (MRI) captured the transition between the invasive and quiescent phase of the infection, revealing the concurrent presence of meningitis and small cysts. During the quiescent phase, in all animals, neurological symptoms disappeared, and cerebrospinal fluid was unremarkable while cysts grew progressively. Subsequently, the onset of neurological symptoms coincided with MRI signs of diffuse or localized increase of intracranial pressure, as confirmed by direct intracranial pressure measuring. All the animals had an excellent post-surgical recovery. This is the first report describing the evolution of coenurosis in vivo. Sequential imaging allowed describing interesting such as the death of some coenuri and different parasite growth rate in the same host.

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mentioning

confidence: 61%

Clinical evolution of cerebral coenurosis from invasive to chronic infection in sheep and a goat

Evangelisti

Varcasia

Deiana

et al. 2016

J Infect Dev Ctries

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“…Ultrasonography has also been used, but it provides very limited information about the location of the cysts (Biswas 2013). Other ancillary tests such as analysis of the serum creatine phosphokinase isoenzyme (CK-BB) and intradermal injection of coenurus cyst fluid (gid test) have also been used but did not provide consistent results (Paltrinieri et al 2010;Scott 2012). The response to skin tests in the gid test has been reported as inconsistent and with low specificity, probably because of cross-reactions with heterologous metacestode infections (Godara et al 2011).…”

Section: Discussionmentioning

confidence: 99%

“…Other signs include grinding of the teeth, salivation, exophthalmos, and nystagmus, and finally, the animals become recumbent, exhibit extensor rigidity and paddle frequently with the hind limbs, and eventually die. When the metacestode localizes in the spinal cord, it results in progressive paresis or hind leg paralysis (Scott 2012). Clinical diagnosis of cerebral coenurosis is based on the physical and neurological examinations.…”

Section: Introductionmentioning

confidence: 99%

Application of polymerase chain reaction on cerebrospinal fluid for diagnosis of cerebral coenurosis in small ruminants

et al. 2015

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Sheep and goats serve as intermediate hosts for the canine tapeworm Taenia multiceps. The cysts produced by the intermediate stage of parasite are usually found in the cerebral hemispheres of small ruminants, and the resulting disease is commonly known as coenurosis. Coenurosis is clinically manifested in the form of various nervous symptoms, depending on the exact location of the cyst. The variety of neurological symptoms contributes to the complexity of clinical diagnosis and reinforces the need for a more specific and acceptable diagnostic approach. We demonstrated here, for the first time, that the T. multiceps DNA is present in the cerebrospinal fluid (CSF) of the infected sheep and goats. In addition, the molecular genetic marker of the mitochondrial DNA was applied phylogenetically to show that our isolates together with other T. multiceps strains comprised a monophyletic group that is a sister to Taenia krabbei. Pairwise comparison between the cox1 sequences of our study and other T. multiceps genotypes existing in the GenBank showed similarity ranging from 98 to 100%. Accordingly, the polymerase chain reaction (PCR) can be used for amplification of DNA of the parasite originated from the CSF and provides a valuable method for accurate identification of coenurosis cases.

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“…Τα κλινικά νευρολογικά ευρήματα είναι χαρα-κτηριστικά της ύπαρξης χωροκατακτητικής αλλοίω-σης στον εγκέφαλο, ποικίλλουν δε ανάλογα με την ακριβή εντόπιση της κύστης στο κεντρικό νευρικό σύστημα (komnenou et al 2000, Giadinis et al 2006, Scott 2012 (Εικ. 5, 6).…”

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“…Στη διά-γνωση μπορούν να συμβάλουν τα ευρήματα της εξέτασης του εγκεφαλονωτιαίου υγρού (komnenou et al 2000(komnenou et al , Scott 2012, αν και ο καλύτερος τρόπος για να επιτευχθεί ακριβής διάγνωση της νόσου σε ζωντανό ζώο είναι με αξονική ή μαγνητική τομο-γραφία (Pau et al 1987, Gonzalo-Orden et al 1999, Scott 2012. Για τη διάγνωση, μπορεί επίσης να εφαρμοστούν, χωρίς όμως μεγάλη αξιοπιστία, η υπερηχοτομογραφία κεφαλής (Doherty et al 1989, Scott 2012) και η ακτινογραφία κεφαλής (Tirgari et al 1987). Πρόσφατα, μελετήθηκε η διαγνωστική αξία του προσδιορισμού των ισοενζύμων Ck-MM και Ck-BB του ενζύμου κρεατινική κινάση συγκρι-τικά με τη συνολική δραστηριότητα αυτού στο αίμα, μέθοδος όμως που δεν βρέθηκε να συμβάλλει ιδι-αίτερα στη διάγνωση της νόσου (Paltrinieri et al 2010).…”

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Differential diagnosis of neurological diseases of small ruminants

Giadinis

Polizopoulou

Fthenakis

2017

J Hellenic Vet Med Soc

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Objective of the present review is the description of diagnostic approach in neurological cases in small ruminants. To improve description purposes in the present paper, neurological disorders of small ruminants are classified as follows: (a) congenital neurological disorders (vitamin A deficiency, copper deficiency, disorders of viral aetiology [including border disease and Schmallenberg disease], disorders with a genetic background), (b) acquired neurological disorders with an acute course (acute coenurosis, Aujeszky’s disease, bacterial meningoencephalitis, botulism, copper deficiency, copper poisoning, disorders following injury, hypocalcaemia, hypomagnesaemia, listeriosis, louping-ill, rare disorders of parasitic aetiology, pregnancy toxaemia, rabies, tetanus, tick paralysis, toxicoses, type D enterotoxaemia, vitamin B1 deficiency) and (c) acquired neurological disorders with a long-standing course (caprine arthritis-encephalitis, central nervous system abscesses, chronic coenurosis, neoplastic disorders, ovine lentiviral encephalomyelitis, scrapie).

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Diagnosis and treatment of coenurosis in sheep

Cited by 39 publications

References 12 publications

Clinical evolution of cerebral coenurosis from invasive to chronic infection in sheep and a goat

Clinical evolution of cerebral coenurosis from invasive to chronic infection in sheep and a goat

Application of polymerase chain reaction on cerebrospinal fluid for diagnosis of cerebral coenurosis in small ruminants

Differential diagnosis of neurological diseases of small ruminants

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