Diagnosis and Treatment of Hypopituitarism

Results of Partial Gastrectomy in Treatment of Peptic Ulcer

“…When cortisone was given there was a prompt water diuresis and the plasma sodium concentration rose to normal, though there was little change in the total body sodium. Water retention may not be very rare in anterior hypopituitarism, although it appears to have been reported as such in only one other case (Whittaker and Whitehead, 1954).…”

Case of Hypopituitary Coma with Serial Electroencephalography

“…Care should be taken to avoid local burns, hyperthermia, and perhaps verv rapid temperature changes. Water retention as a cause of death in anterior hypopituitarism was first described by Whittaker and Whitehead (1954), and is not easily diagnosed. Gross changes in the level of consciousness may occur with small water loads -for example, 1 litre.…”

Treatment of Hypopituitarism

“…Sheehan and Summers (1954) report on the excellent response obtained in four cases treated with cortisone alone. On the other hand, Perkins and Rynearson (1952), Hart (1953), Querido et al (1954, Whittaker and Whitehead (1954), and others advocate a wider range of substitution therapy and include deoxycortone acetate (D.C.A. ), testosterone, and thyroid in addition to cortisone.…”