Diagnosis and treatment of Staphylococcus aureus infections of the skin and mucous membranes

Antimicrobial resistance of Staphylococcus aureus isolated from skin infections and its implications in various clinical conditions in Korea

“…Usually, either penicillin or cephalosporin is initially recommended for MSSA skin infections . However, MRSA is known to show resistance to nearly all β ‐lactam antimicrobials and to some non‐ β ‐lactam agents, which complicates the appropriate selection of antimicrobial agent .…”

Early clinical assessment of response to treatment of skin and soft-tissue infections: how can it help clinicians? Perspectives from Europe

“…Additional antibiotics recommended by guidelines for cSSTI with proven or suspected MRSA involvement include linezolid, daptomycin and tigecycline (Table 2), with 7-14 days of therapy generally being recommended [35,36,38,[40][41][42][43]. Several new antibiotics approved in Europe for the treatment of ABSSSIs (oritavancin, dalbavancin and tedizolid phosphate) [19][20][21] or cSSTI (ceftaroline) [44] are not yet discussed in European guidelines.…”

Are two penicillins better than one? A systematic review of oral flucloxacillin and penicillin V versus oral flucloxacillin alone for the emergency department treatment of cellulitis

“…In Germany, group 1 cephalosporins (cephalexin) are recommended as first-line agents for severe impetigo and furunculosis, and oral clindamycin is recommended as the first-line treatment for mild to moderate cellulitis [3]. For more severe infections, intravenous flucloxacillin or a second-generation cephalosporin is recommended.…”

“…It is on a spectrum of disease from mild infections, easily treatable with oral antibiotics, to severe necrotizing infections with associated high mortality [2]. Although a different entity, the term cellulitis is often used interchangeably with erysipelas [1], is known as 'localized phlegmon' in Germany [3] and falls under the umbrella term of 'skin and soft tissue infections' (SSTI).…”