Diagnosis of interstitial lung disease

Bush, Andrew

doi:10.1002/1099-0496(199608)22:2<81::aid-ppul1950220204>3.0.co;2-8

Cited by 31 publications

(26 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Brogan and RaZes have made a useful contribution to more reliable diagnosis. 1 However, I feel that their finding of 9% could represent a falsely low proportion of children with serious bacteraemia because of potential recruitment bias and measurement bias.…”

Section: Repliesmentioning

confidence: 95%

See 1 more Smart Citation

Varicella-zoster virus.

FINN¹

2001

Archives of Disease in Childhood

View full text Add to dashboard Cite

Section: Repliesmentioning

confidence: 95%

“…1 This is an important audit for many general paediatricians in the UK. In Newcastle 36% of children with petechiae were treated with antibiotics, and only 10% had meningococcal disease (MCD).…”

mentioning

confidence: 99%

Varicella-zoster virus.

FINN¹

2001

Archives of Disease in Childhood

View full text Add to dashboard Cite

“…Percutaneous biopsy has been used in some centres [31,32], but is not the optimal technique [33,34]: the child requires a full general anaesthetic; the pieces of tissue, although obtained under CT control, are not taken under direct vision; and, because the procedure is blind and uncontrolled, there is an unacceptable incidence of bleeding and pneumothorax. Biopsy of the lung under direct vision is safe, well tolerated and should be regarded as the gold standard.…”

Section: Invasive Diagnosismentioning

confidence: 99%

Paediatric interstitial lung disease

Bush

2005

Breathe

View full text Add to dashboard Cite

Key pointsPresentation of ILD is very non-specific.Imaging, especially HRCT, confirms the presence of ILD, but is rarely diagnostic.Invasive diagnosis is almost always needed.Bronchoscopy rarely gives diagnostic information in paediatric ILD.For most paediatric ILD, transbronchial or percutaneous lung biopsy gives insufficient tissue for diagnosis and carries increased risk.Open lung biopsy or VATS is the diagnostic investigation of choice.Educational aimsTo allow the reader to correctly identify infants and children with interstitial lung disease (ILD).To help the reader to appreciate the wide differential diagnosis, including that of disorders specific to infancy, comprising the surfactant protein disorders.To explain the strengths and weaknesses of the different investigative modalities used in establishing a firm diagnosis.To discuss the limited evidence for the different treatment options currently in use.SummaryPaediatric interstitial disease is rare, and comprises many disparate diseases. This article aims to provide the reader with an update on how to recognise infants and children who should be considered as possibly having ILD. The diagnostic process, including the roles of HRCT and bronchoscopy, and the different methods of lung biopsy, will be set out. The newly recognised entities, such as neuroendocrine cell hyperplasia of infancy, pulmonary interstitial glycogenosis and the disorders of surfactant protein metabolism, are also described. Finally, the article reviews the evidence that exists to guide treatment of these conditions.

show abstract

“…The blind treatment of all cases with corticosteroids is unacceptable due to the increased morbidity associated with treatment, and also due to the fact that not all cases respond [43]. In addition, alternative therapies may be appropriate, e.g.…”

Section: Diffuse Interstitial Lung Diseasementioning

confidence: 99%

High-resolution CT of paediatric lung disease

Copley

Padley

2001

Eur Radiol

View full text Add to dashboard Cite

High-resolution computed tomography (HRCT) has improved our understanding of many lung diseases in adults. The technique is used less often in children due to concerns regarding radiation dose. However, HRCT may provide important diagnostic information in a variety of lung diseases in children including airways diseases and diffuse interstitial lung disease. This review illustrates the HRCT appearances of a variety of conditions and describes the emerging role of the technique in children.

show abstract

Diagnosis of interstitial lung disease

Cited by 31 publications

References 21 publications

Varicella-zoster virus.

Varicella-zoster virus.

Paediatric interstitial lung disease

High-resolution CT of paediatric lung disease

Contact Info

Product

Resources

About