2021
DOI: 10.1016/j.vetpar.2021.109517
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Diagnosis of sheep fasciolosis caused by Fasciola hepatica using cathepsin L enzyme-linked immunosorbent assays (ELISA)

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Cited by 23 publications
(25 citation statements)
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“… Life stages of F. hepatica and F. gigantica. A: Liver from an infected sheep with acute F. hepatica infection (reported by López Corrales et al [ 157 ]) showing gross pathology. The white tracks delineate the tunneling activity of the parasites through the liver tissues, most commonly observed on the left lobe of liver closest to the intestine in situ (LL).…”
Section: Fasciola Spp Lifecycle and Biologymentioning
confidence: 99%
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“… Life stages of F. hepatica and F. gigantica. A: Liver from an infected sheep with acute F. hepatica infection (reported by López Corrales et al [ 157 ]) showing gross pathology. The white tracks delineate the tunneling activity of the parasites through the liver tissues, most commonly observed on the left lobe of liver closest to the intestine in situ (LL).…”
Section: Fasciola Spp Lifecycle and Biologymentioning
confidence: 99%
“…Enzyme-linked immunosorbent assays (ELISAs) such as the coproantigen-ELISAs offer an alternative method of diagnosis from FEC, but they are limited in detecting infection inside the pre-patent period [ 101 , 102 ]. Of the methods mentioned in Table 2, only serological ELISAs were proven to detect specific anti- F. hepatica antibodies as early as ~3 weeks post-infection [ 103 , 104 ]; however, this method cannot distinguish between new and historic infections. Diagnosis can be complemented by considering nonspecific symptoms, namely increased liver enzymes in serum (i.e., ALT, AST, GGT, LDH and AP), anemia and decreased serum albumin levels.…”
Section: Pathogenicity Of Fasciola Spp In Their Definitive Hostsmentioning
confidence: 99%
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