Diagnosis of the Intraductal Component of Invasive Breast Cancer

Kang, Doo Kyoung; Jeon, Gyeong Sik; Yim, Hyunee; Jung, Yuh‐Seog

doi:10.7863/jum.2007.26.11.1587

Cited by 22 publications

(15 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Breast microcalcifications are considered an important finding for the diagnosis of breast cancer, making their correct visualization and analysis crucial for early detection. [5][6][7][8][9][11][12][13][24][25][26][27][28][29][30][31] Mammography is considered the only reliable method to identify and classify microcalcifications. [1][2][3][4][5][6][7][8][9][10][11][12] Current US technology is not considered a reliable method for the detection or evaluation of microcalcifications.…”

Section: Discussionmentioning

confidence: 99%

“…Clinical evaluation of breast microcalcifications by gray scale ultrasound imaging (US) is not usually performed, due to the limitations of this imaging technique in identifying microcalcifications. There have been some attempts by researchers to use gray scale US to identify microcalcifications, but even the most promising results from these studies/methods do not support the clinical use of gray scale US for the evaluation of microcalcifications 4 , 5 , 7 – 9 , 11 – 13 , 15 , 26 – 29 , 32 , 33 …”

mentioning

confidence: 99%

“…There have been some attempts by researchers to use gray scale US to identify microcalcifications, but even the most promising results from these studies/methods do not support the clinical use of gray scale US for the evaluation of microcalcifications. 4,5,[7][8][9][11][12][13]15,[26][27][28][29]32,33 Research has shown that when microcalcifications lie within a mass, they are easier to visualize with gray scale US, since the mass in question works as an acoustic window. The microcalcifications appear on gray scale US as hyperechoic foci, which usually do not have an acoustic shadow.…”

mentioning

confidence: 99%

“…1,[3][4][5][7][8][9]11,12,29,33,34 However, the evaluation of isolated and/or clusters of microcalcifications that lie within normal breast tissue is considered to be more difficult to accomplish with gray scale US, due to the lack of contrast between normal parenchyma and the microcalcifications. [2][3][4][5][7][8][9][11][12][13][26][27][28]32,33 Ultrasound is used to guide percutaneous core biopsies or wire localizations for surgical biopsies of breast masses. For the patients, there are many advantages to a US-guided procedure compared with a mammographically guided procedure.…”

mentioning

confidence: 99%

See 3 more Smart Citations

New Image Processing Technique for Evaluating Breast Microcalcifications

Machado

Eisenbrey

Cavanaugh

et al. 2012

Journal of Ultrasound in Medicine

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

New Image Processing Technique for Evaluating Breast Microcalcifications

Machado

Eisenbrey

Cavanaugh

et al. 2012

Journal of Ultrasound in Medicine

View full text Add to dashboard Cite

show abstract

“…It has been widely reported that ultrasonography is more sensitive than mammography in breast cancer diagnosis (Kang et al, 2007;Huang et al, 2012;Lehman et al, 2012;Ya-Jie et al, 2012). Although the specificity of mammography is higher than that of ultrasonography (Birdwell, 2009), in the view of breast cancer screening, the higher sensitivity is more beneficial for early diagnosis of breast cancer.…”

Section: Introductionmentioning

confidence: 99%

Effects of Age, Breast Density and Volume on Breast Cancer Diagnosis: A Retrospective Comparison of Sensitivity of Mammography and Ultrasonography in China's Rural Areas

Wang¹,

Chen²,

Yin³

et al. 2013

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Purpose: Mammography has been confirmed as the only effective mode to improve the prognosis of patients with breast cancer in Western developed countries, but might not be a good choice in other areas of the world. One of the major challenges in China is to determine an optimal imaging modality for breast cancer screening. This study was designed to clarify the sensitivity of ultrasonography compared with that of mammography in rural China. Methods: We retrospectively studied the sensitivity of mammography and ultrasonography based on 306 breast cancer patients detected by the program of "screening for cervical cancer and breast cancer" performed in Chinese rural areas between January 2009 and December 2011, and analyzed the effects of age, breast density and volume on the sensitivity. Results: Stratified analysis showed that the sensitivity of breast ultrasonography was significantly higher than that of mammography in premenopausal patients (81.4% vs. 61.1%, p=0.02), in women ≤ 55 years of age (82.2% vs. 63.4%, p<0.01), in the high breast density group (American College of Radiology [ACR] levels 3-4) (85.9% vs. 60.6%, p<0.01) and in the small breast volume group (≤400 ml) (87.1% vs. 66.7%, p<0.01). Age had a significant effect on sensitivity of mammography (breast density and volume-adjusted odds ratio, 6.39; 95% confidence interval, 2.8-14.4 in age group > 55 compared to age group ≤ 45), but not that of ultrasonography. Neither breast density nor volume had significant effect on sensitivity of mammography or ultrasonography. Conclusions: Ultrasonography is more sensitive than mammography in detecting breast cancer in women under 55 year-old Chinese, especially in those with high-density and relatively small breasts.

show abstract

Characterization of Breast Microcalcifications Using a New Ultrasound Image‐Processing Technique

Machado

Eisenbrey

Stanczak

et al. 2018

J of Ultrasound Medicine

View full text Add to dashboard Cite

Objectives-To evaluate a new commercial image-processing technique (MicroPure; Toshiba America Medical Systems, Tustin, CA) for detection and characterization of breast microcalcifications in patients undergoing stereotactic or ultrasound-guided biopsies using mammography as the reference standard.Methods-One hundred female patients, with a total of 104 lesions, scheduled for an image-guided biopsy of an area with breast microcalcifications (identified on a prior mammogram) underwent MicroPure examinations of the breast using an Aplio XG scanner (Toshiba America Medical Systems) with a broadbandwidth linear array. MicroPure combines nonlinear imaging and speckle suppression to mark suspected calcifications as white spots in a blue overlay image. Four independent and blinded readers (2 radiologists and 2 physicists) analyzed 208 digital clips consisting of dual grayscale ultrasound and MicroPure imaging, counting the number of microcalcifications seen with MicroPure. The observers also assessed the level of suspicion on a qualitative, visual analog, 6-point scale from 0 (no findings) over 1 (benign) to 5 (malignant).Results-The mean number of microcalcifications ± SD seen was 6.3 ± 3.5, whereas mammography saw 28.9 ± 24.6 (P = .66). When the MicroPure level of suspicion scores were compared with pathologic results using a receiver operating characteristic curve analysis, the areas under the curve ranged from 0.54 to 0.59. Nonetheless, malignant cases were seen to have significantly more microcalcifications than benign cases (mean number of microcalcifications, 6.9 ± 5.1 versus 5.3 ± 3.7; P = .02).Conclusions-MicroPure can be used to identify areas with breast microcalcifications but cannot effectively characterize such areas. Instead, MicroPure may represent a new imaging method for guiding a biopsy to areas of microcalcifications.T he use of mammography is established as a screening method for breast cancer with high sensitivity (63%-96%) and specificity (87%-97%), and it is also the reference standard for detection of breast microcalcifications, 1-8 which are considered important findings for the diagnosis of breast cancer. 3,[9][10][11][12][13][14][15][16] Mammography is also used to assess the morphologic characteristics of calcifications and to assign a level of suspicion (LOS).

show abstract

Diagnosis of the Intraductal Component of Invasive Breast Cancer

Abstract: Combined assessment with mammography and sonography offers more accurate information for the presence of an intraductal component and the extent of a tumor than each separate assessment.

Cited by 22 publications

References 40 publications

New Image Processing Technique for Evaluating Breast Microcalcifications

New Image Processing Technique for Evaluating Breast Microcalcifications

Effects of Age, Breast Density and Volume on Breast Cancer Diagnosis: A Retrospective Comparison of Sensitivity of Mammography and Ultrasonography in China's Rural Areas

Characterization of Breast Microcalcifications Using a New Ultrasound Image‐Processing Technique

Contact Info

Product

Resources

About