Diagnosis of Type 2 Diabetes and Pre-diabetes Using Machine Learning

Severeyn, Erika; Wong, Sara; Velásquez, Jesús; Perpiñán, Gilberto; Herrera, Huamán; Altuve, Miguel; Díaz, José A.

doi:10.1007/978-3-030-30648-9_105

Cited by 8 publications

(1 citation statement)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Using an in-house-developed algorithm, all possible combinations of the features were found and scored (silhouette value). Then, all combinations with silhouette values above 0.6, which indicates a good clustering (i.e., clusters are well-separated) [ 26 , 27 , 28 ], for a range of cluster numbers ( k = 2 to k = 9) were selected for both the blue and red light conditions, and the best common combinations in both conditions were identified. Finally, using unsupervised ML, a variety of different clustering methods were used to classify subjects.…”

Section: Methodsmentioning

confidence: 99%

Intersubject Variability in Cerebrovascular Hemodynamics and Systemic Physiology during a Verbal Fluency Task under Colored Light Exposure: Clustering of Subjects by Unsupervised Machine Learning

et al. 2022

View full text Add to dashboard Cite

There is large intersubject variability in cerebrovascular hemodynamic and systemic physiological responses induced by a verbal fluency task (VFT) under colored light exposure (CLE). We hypothesized that machine learning would enable us to classify the response patterns and provide new insights into the common response patterns between subjects. In total, 32 healthy subjects (15 men and 17 women, age: 25.5 ± 4.3 years) were exposed to two different light colors (red vs. blue) in a randomized cross-over study design for 9 min while performing a VFT. We used the systemic physiology augmented functional near-infrared spectroscopy (SPA-fNIRS) approach to measure cerebrovascular hemodynamics and oxygenation at the prefrontal cortex (PFC) and visual cortex (VC) concurrently with systemic physiological parameters. We found that subjects were suitably classified by unsupervised machine learning into different groups according to the changes in the following parameters: end-tidal carbon dioxide, arterial oxygen saturation, skin conductance, oxygenated hemoglobin in the VC, and deoxygenated hemoglobin in the PFC. With hard clustering methods, three and five different groups of subjects were found for the blue and red light exposure, respectively. Our results highlight the fact that humans show specific reactivity types to the CLE-VFT experimental paradigm.

show abstract

Section: Methodsmentioning

confidence: 99%