1999
DOI: 10.1080/17453674.1999.11744823
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Diagnosis, treatment and prognosis of patients with synovial sarcoma

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Cited by 4 publications
(1 citation statement)
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“…Synovial sarcomas are high‐grade malignant tumors with a poor prognosis, accounting for 5% to 10% of all soft tissue sarcomas, mostly in younger patients 25. They carry a pathognomonic chromosomal alteration, t(X;18),26, 27 representing a rearrangement involving the SYT gene on chromosome 18 and 1 of 5 SSX genes on chromosome X 28–30. The presence of the translocation can be determined by RT‐PCR of the chimeric SYT‐SSX transcript,28, 29, 31–33 and the translocation type corresponds to the SSX gene involved in the gene rearrangement.…”
mentioning
confidence: 99%
“…Synovial sarcomas are high‐grade malignant tumors with a poor prognosis, accounting for 5% to 10% of all soft tissue sarcomas, mostly in younger patients 25. They carry a pathognomonic chromosomal alteration, t(X;18),26, 27 representing a rearrangement involving the SYT gene on chromosome 18 and 1 of 5 SSX genes on chromosome X 28–30. The presence of the translocation can be determined by RT‐PCR of the chimeric SYT‐SSX transcript,28, 29, 31–33 and the translocation type corresponds to the SSX gene involved in the gene rearrangement.…”
mentioning
confidence: 99%