2015
DOI: 10.1186/s13643-015-0109-0
|View full text |Cite
|
Sign up to set email alerts
|

Diagnostic accuracy of fine needle aspiration biopsy for detection of malignancy in pediatric thyroid nodules: protocol for a systematic review and meta-analysis

Abstract: BackgroundFine needle aspiration biopsy (FNAB) is an accurate test commonly used to determine whether thyroid nodules are malignant in adults. However, less is known about its diagnostic accuracy for this purpose in children, where conduct of FNAB is less frequent, more technically challenging, and pre-test probabilities of malignancy are often higher. The purpose of this systematic review is to evaluate the diagnostic accuracy of FNAB for the detection of malignancy in pediatric thyroid nodules.MethodsWe will… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

1
15
0

Year Published

2016
2016
2023
2023

Publication Types

Select...
4
2

Relationship

0
6

Authors

Journals

citations
Cited by 11 publications
(16 citation statements)
references
References 52 publications
1
15
0
Order By: Relevance
“…FNA as an important tool in the cytologic assessment of pediatric thyroid nodules provides 94% sensitivity, 81% specificity, and 77.2%‐98.6% diagnostic accuracy . Similar to the management of adult thyroid nodules, the real challenge is identification of malignancy among the indeterminate categories.…”
Section: Discussionmentioning
confidence: 99%
“…FNA as an important tool in the cytologic assessment of pediatric thyroid nodules provides 94% sensitivity, 81% specificity, and 77.2%‐98.6% diagnostic accuracy . Similar to the management of adult thyroid nodules, the real challenge is identification of malignancy among the indeterminate categories.…”
Section: Discussionmentioning
confidence: 99%
“…At our institution, FNA was not readily available in approximately the first 10 years of the data collected, which is not considered standard practice [18]. The current standard at our institution is to perform an ultrasound guided FNA prior to the consideration of surgical management.…”
Section: Limitationsmentioning
confidence: 97%
“…In addition, these authors demonstrated that 75% of thyroid nodules were benign, so the combined use of neck ultrasonography and FNAC would optimize accuracy and safety and result in a reduction of the overestimated risk of cancer and the consequently high percentage of useless thyroidectomies. In fact, a recent meta‐analysis and several series have estimated that FNAC has 94% sensitivity and 81% specificity for pediatric thyroid nodules and that the accuracy rate is between 77.2% and 98.6% …”
Section: The Role Of Fnac In Pediatric Series: Evidence From the Litementioning
confidence: 99%
“…Although the results of a recent meta‐analysis study concluded that FNAC is a highly sensitive tool for discriminating between benign and malignant nodules, most series have not focused on the diagnostic relevance of the identification of different malignant histotypes on thyroid FNAC . One of the main reasons for this could be the clearly assessed evidence showing that the most frequent thyroid cancer is the classic variant of PTC; therefore, few series have described other variants and/or entities .…”
Section: Malignancies and Pediatric Seriesmentioning
confidence: 99%
See 1 more Smart Citation