Diagnostic accuracy of Schistoso
 ma
 ICT Ig
 G
 -
 IgM and comparison to other used techniques screening urinary schistosomiasis in Nigeria

Houmsou, R. S.; Wama, B. E.; Agere, Hemen; Uniga, John Ador; Jerry, Timothy Jerry; Azuaga, Paul; Amuta, E. U.; Kela, Santaya Larit

doi:10.1515/almed-2020-0093

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…Schistosomiasis is a serious public health for rural inhabitants. They are usually exposed to infection through their agricultural practices of farming rice, recreational and domestic activities, fishing, and swimming in infected ponds or rivers where the snail intermediate hosts breed [10]. Clinical signs and symptoms include dysuria, haematuria, granulomatous host response and urinary egg excretion, renal failure and bladder and other genitourinary cancers [11].…”

Section: Introductionmentioning

confidence: 99%

Current trends in the laboratory diagnosis of schistosomiasis infection

Imam,

Sirajo,

Obeagu

2024

NIJRMS

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Schistosomiasis is a neglected tropical disease that affects about 290 million patients worldwide. Children aged between 5 and 14 years represent 45.8% of the affected patients, in addition, schistosomiasis has been reported in Schistosoma-free areas, mostly because of tourism and immigration from endemic countries. Intestinal schistosomiasis caused by Schistosoma mansoni is mainly diagnosed via direct stool examination for egg detection. Immunological methods are favoured for disease monitoring and preliminary checking for communities in areas with low infection rates, and for patients with light and chronic infections where parasitological tests are negative. PCR-based diagnostic techniques are more sensitive, but expensive. Tegument proteins and miRNAs are promising markers for diagnosis of schistosomiasis. Keywords: Schistosomiasis, Diagnosis and current trends

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Section: Introductionmentioning

confidence: 99%

Current trends in the laboratory diagnosis of schistosomiasis infection

Imam,

Sirajo,

Obeagu

2024

NIJRMS

View full text Add to dashboard Cite

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Diagnostic accuracy of Schistosoma immunochromatographic IgG/IgM rapid test in the detection of schistosomiasis in Zambia

Mudenda

Hamooya

Tembo

et al. 2022

JoBAZ

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Background Schistosomiasis or bilharzia is one of the neglected tropical diseases affecting over 230 million people globally. In Zambia, the infection poses as one of the major public health burdens among parasitic infections. The diagnosis of schistosomiasis in endemic countries is still a challenge. The aim of this study was to evaluate the diagnostic performance of the Schistosoma immunochromatographic (ICT) IgG–IgM rapid diagnostic test in the detection of schistosome infections from Schistosoma haematobium and mansoni in Siavonga district in Zambia. Results The diagnostic performance of Schistosoma ICT IgG–IgM test was evaluated using 430 of the 440 participants’ samples which had complete data. The prevalence of S. haematobium and S. mansoni was 4.4% and 6%, respectively, while seroprevalence was 71.4%. The sensitivity and specificity of the Schistosoma ICT IgG–IgM test was found to be 100% and 32.2%, respectively. The associated positive predictive value was 13.8% and 100% for negative predictive value. Diagnostic accuracy [area under the curve (AUC)] was 0.57 [95% confidence interval (CI) 0.52, 0.62]. Conclusions The Schistosoma ICT IgG–IgM proved to have remarkably high sensitivity with a fairly good specificity and diagnostic accuracy for the detection of both urinary and intestinal schistosomiasis. We therefore recommend the test as it is ideal for screening in the light of current focus of disease elimination in endemic countries.

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Diagnostic accuracy of Schistoso ma ICT Ig G - IgM and comparison to other used techniques screening urinary schistosomiasis in Nigeria

Cited by 2 publications

References 23 publications

Current trends in the laboratory diagnosis of schistosomiasis infection

Current trends in the laboratory diagnosis of schistosomiasis infection

Diagnostic accuracy of Schistosoma immunochromatographic IgG/IgM rapid test in the detection of schistosomiasis in Zambia

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