Diagnostic accuracy of lymphoma established by fine-needle aspiration cytological biopsy

Delyuzar,; Amir, Zainuddin; Suryadi, Dedy

doi:10.1088/1755-1315/125/1/012136

Cited by 1 publication

(3 citation statements)

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“…Meanwhile, in another study, the age range of malignant tumor cases was in the 41-60 age range. Based on a study conducted by patients with lymphadenopathy over the age of 40 years, the risk of malignancy was 4% when compared to those aged less than 40 years who had a risk of malignancy of only 0.4% [17]. Malignant cases often occur in elderly patients because they are associated with organ responses to infection [15].…”

Section: Discussionmentioning

confidence: 99%

“…The sensitivity value, the specifity value, the positive predictive value, the negative predictive value, the accuracy of the results , is 82.5%, 96,15%, 97,5%, 78,12%, 87,87%. In general, it can be stated that colli lymphadenopathy examination with FNAB can be a screening diagnostic tool in helping to establish the diagnosis of colli lymphadenopathy [17]. In future research, a likelihood ratio indicator can be added as a complementary data support to provide optimal results for the combination of screening tests.…”

Section: Discussionmentioning

confidence: 99%

“…Many studies have found that the diagnostic value of FNAB varies, this can be influenced by several factors, such as sample adequacy, superinfection, fibrosis, clinical and radiological information, pathologist experience in interpreting cytological specimens, and staining methods can affect diagnostic value [16]. So that on inspection FNAB colli lymphadenopathy is almost always followed by an open biopsy [17].…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic Test Fine Needle Aspiration Biopsy (FNAB) Examination on Gold Standard Histopathological Tests for Identification of Colli Lymphadenopathy Patients at RSPAL. Dr. Ramelan Surabaya

Andhika¹,

Handayati²,

Woelansari³

2023

International Journal of Advanced Health Science and Technology

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Lymphadenopathy is a common clinical manifestation which requires rapid and accurate diagnosis. Fine Needle Aspiration Biopsy (FNAB) is used as an initial and direct diagnosis in cases of lymphadenopathy, confirmatory diagnosis of colli lymphadenopathy is carried out by histopathological examination. The purpose of this study was to determine the value of the FNAB diagnostic test for lymphadenopathy colli FNAB against the gold standard histopathology of Paraffin Blok for benign and malignant lymphadenopathy. This type of research is observational descriptive by taking medical record data (SIM-RS) of patients with lymphadenopathy in the colli region who were examined for FNAB and histopathology at the Anatomical Pathology Laboratory Installation, RSPAL dr. Ramelan Surabaya for the period January 2019 – March 2022. The sample used was selected using the total sampling method, obtained as many as 66 samples that met the inclusion criteria. The results of the FNAB examination were then matched against the histopathological gold standard examination data. Furthermore, the data was processed by 2x2 crosstabulation and diagnostic tests were carried out to determine the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. The results showed that the accuracy of the FNAB diagnostic test was 86.56%, sensitivity 80.48%, specificity 96.15%, positive predictive value 97.05%, negative predictive value 75.75%. In general, it can be stated that the FNAB examination can be a screening diagnostic tool that is easy, fast, relatively affordable and applicable in helping to establish the diagnosis of colli lymphadenopathy.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%