BackgroundIndonesia is the 2nd largest of tuberculous (TB) cases in the world. Therefore, TB must be controlled by increasing the capacity anddeveloping universal access needed for TB diagnose accurately and quickly. Progression in controlling TB and decreasing theconsequence can be accelerated through early detection and promt treatment. This study used PCR test as gold standard, albeitthe high cost. Thus, quick, accurate and low cost diagnostic method is needed. In this case morphologic features requirementinclude the existence of epithelioid and necrosis in FNAB smears. Objective was to analyze morphologic features of tuberculosislymphadenitis using FNAB and PCR methods.MethodsThis study is a cross sectional analysis. N samples are all kind of lymphadenitis tuberculosis. Morphologic features in FNABcytology must be confirmed using PCR test and performing chi-square test respectively.ResultsEpitheloid and necrosis features of TB lymphadenitis on FNAB showed 100% positive on PCR methods. This study divided intothree groups. Statistic analyses between group I and II, group II and III showed in significant differences (p=0.074); while betweengroup I and III showed significant differences (p<0.05).ConclusionsPCR method could confirmed morphologic features (epitheloid and necrosis) of TB lymphadenitis
Background: Basal cell carcinoma (BCC) is an epithelial malignancy most commonly found in human about 75-80% of non-melanoma cancer. At the moment, BCC has been one of the most important health problems, due to increasing number of incidents. Studies about the relationship between clinicopathologic data and histopathologic subtypes of BCC in Indonesia especially in Medan are still limited. Therefore, the researchers are interested in this study. Objective: To analyze the relationship between clinicopathologic data and histopathologic subtypes of BCC. Methods: A cross-sectional study was performed using formalin-fixed tissue paraffin blocks from 38 BCC patients. Clinical data such as age, gender, occupation, ethnic groups, tumour location and size were recorded. Then, each BCC cases were reviewed for determining histopathologic subtypes of BCC. Then, the relationship between clinicopathologic data and histopathologic subtypes in BCC was assassed and analyzed with statistical software by using the chi-square test or fisher exact test. Results and Discussion: About 68.4% samples aged > 60 years old; 57.9% women; 36.8% housewives; 44.7% located in mid face, mostly in palpebra; 50% with size of ≥1.5cm; 78.9% nodular BCC; and 89.5% with lower recurrence risks. Men tend to have BCC than women because they smoke more and tend to work outdoor. That's why they are more exposed to UV rays. These factors are thought to trigger tumour growth. Conclussion: There were no statistically significant relationships between age, gender, occupations, ethnic, tumour location and size with histopathologic subtypes of BCC
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