Diagnostic accuracy of point-of-care tests in acute community-acquired lower respiratory tract infections. A systematic review and meta-analysis

Abstract

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Advances in diagnostic tools for respiratory tract infections: from tuberculosis to COVID-19 – changing paradigms?

“…The main benefits of these assays is that they are portable, miniaturized, low cost and highly integrated POC devices [57]. In the move to a new paradigm of personalized medicine, POC diagnostic testing has been proposed to improve the quality of antibiotic prescription [58] but accuracy is variable and settings need careful adjustment [59].…”

“…Depending on the clinical setting and accessibility, the plain chest radiograph is not always required for diagnosis, nevertheless it still remains a relevant tool. Lung ultrasound has shown better accuracy than chest X-ray for bacterial pneumonia in emergency departments [18] and an advance during the pandemic has been its increased use for both diagnosis and follow-up [19]. The additional value of computed tomography has been widely recognized for COVID-19 pneumonia [20].…”

“…In fact, immune tools measuring T-cell responses and detecting IFN-γ in vitro (IGRAs) have been used for some years to diagnose TB and nowadays they are under investigation for SARS-CoV-2 [54][55][56][57][58][59].…”

“…POC technologies have allowed community-based testing to be scaled up and used as a public health tool, but they need to be linked to careful evaluation [147] and to demonstrate their diagnostic accuracy in clinical practice [59]. Timely results also involve careful interpretation and this is facilitated by effective interdisciplinary communication starting with understandable reporting of results.…”

The correlation between fat-soluble vitamin levels and inflammatory factors in pediatric community-acquired pneumonia : a retrospective study.

“…At present, the diagnosis of CAP mainly depends on the clinical manifestations of patients, chest radiography, and the pathogen detection of respiratory secretions. 4 We hope that there are other aids to diagnose pediatric CAP on the basis of routine diagnosis and treatment. Currently, part of the studies suggest that have shown that the vitamin levels in CAP patients have a certain relationship with the treatment and prevention of the disease.…”