Diagnostic accuracy of upper limb neurodynamic tests for the assessment of peripheral neuropathic pain: a systematic review

Abstract

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Postoperative Pain and Paresthesia in Labral Repairs of the Shoulder: Location Does Matter

“…We did not formally perform nerve conduction studies or magnetic resonance imaging to rule out cervical radiculopathy, carpal tunnel syndrome, and cubital tunnel syndrome, which are known causes of hand paresthesia. 2 However, Koulidis et al 14 recently performed a systematic review evaluating the diagnostic accuracy of neurodynamic tests for the assessment of neuropathic pain. They found that nerve conduction studies alone were not useful in the diagnosis of upper limb neuropathies, including carpal tunnel syndrome and cervical radiculopathy.…”

The effectiveness of early diagnostic tools for neural lesions in leprosy An observational cohort study

“…Leprosy patients test positive when submitted to Neurodynamic Assessment of lower limbs [23] . But, even when the tests do not reproduce the symptoms in the affected nerves, characterizing negative tests, studies suggest that a neuropathy cannot be ruled out yet, this can mean a more severe lesion with demyelination of the fibres [33] (as occurred in degree 2 patients that tested negative in the lower limbs in our analysis), producing a possible false negative result [18] , thus explaining the low sensitivity of the NDA in lower limbs, because low sensitivity produces more false negative results [18] .…”

“…perpetuity. preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in The copyright holder for this this version posted November 22, 2020. ; https://doi.org/10.1101/2020.11.19.20234963 doi: medRxiv preprint 21 DISCUSSION __________________________________________________________________________________ differential diagnosis, where the combination of negative neurodynamic test results could be used to rule out a disorder in the peripheral nerves; with limited evidence, they are relevant in cervical radiculopathies [ 33] .…”

Nerve pathology and neuropathic pain after whiplash injury: a systematic review and meta-analysis

“…Consistent with this, PPT over peripheral nerves has shown heightened sensitivity in both neuropathic 16,33,34 and traditionally nonneuropathic pain conditions, such as tension-type headache 12 and epicondylalgia. 34 Furthermore, upper-limb neurodynamic tests do not demonstrate diagnostic accuracy in detecting peripheral neuropathic pain 58 as they can be negative in patients with clear nerve involvement 4 or positive in patients with traditionally nonneuropathic conditions such as nonspecific neck and arm pain 72 and fibromyalgia. 118 Therefore, although the findings of heightened nerve mechanosensitivity in WAD are intriguing and warrant further exploration, care must be taken in their interpretation regarding neuropathic pain or structural nerve pathology.…”