Diagnostic and Interventional Radiology in Idiopathic Granulomatous Mastitis

Durur-Subasi, İrmak

doi:10.5152/eurasianjmed.2019.19211

Cited by 13 publications

(16 citation statements)

References 17 publications

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“…There is no consensus on disease management [1,3]. Two options are proposed in the literature [4][5][6][7]: corticosteroids versus a surgical approach. Corticosteroid therapy is a noninvasive treatment; it is effective in the treatment of IGM by reducing the lesion size and extent.…”

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Idiopathic Granulomatous Mastitis with Oral Prednisolone

Chiguer¹,

Farid²,

Dref³

et al. 2020

SJMCR

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Idiopathic granulomatous mastitis was first described in 1972 by Kessler and Wolloch. It is a rare breast condition of unknown etiology. The challenge is to differentiate it most importantly from breast cancer and other causes of mastitis. In this report, we describe a successful response of idiopathic granulomatous mastitis to oral prednisolone (1mg/kg/day).The patient showed a significant decrease in the size of lesion with significant reduction in intensity of color and thickness, until almost total disappearance. Our experience suggests that steroid therapy may be recommended in all cases of idiopathic granulomatous mastitis as the first-line therapy.

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Section: Discussionmentioning

confidence: 99%

Successful Treatment of Idiopathic Granulomatous Mastitis with Oral Prednisolone

Chiguer¹,

Farid²,

Dref³

et al. 2020

SJMCR

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“…Several precipitating factors have been proposed; it includes pregnancy, lactation, hyperprolactinemia, α1-antitrypsin deficiency, oral contraceptive use, trauma, diabetes, autoimmune disease, and smoking. Hyperprolactinemia and smoking and are the only factors with well-established associations with GM [ 5 , 6 ]. Several mechanisms were proposed, non-yet is proven.…”

Section: Pathophysiologymentioning

confidence: 99%

“…External draining sinuses, erythema and edema also reported [ 38 ].The nipple is rarely involved, although nipple retraction and ulceration and discharge have been documented ( 4 ). Patients may also have more bizarre presentations, particularly in subclinical forms [ 5 , 13 ] Nevertheless, systemic symptoms such as fever are generally not present [ 43 ].Although very rare, it can also be seen in male patients [ [37] , [40] ].…”

Section: Clinical Presentationmentioning

confidence: 99%

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Assertive clinical practice in managing patients with idiopathic granulomatous mastitis: Review of literature

Alsaleh

2021

Annals of Medicine and Surgery

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Idiopathic granulomatous mastitis (IGM) is a benign persistent inflammatory breast entity characterized histologically by lobulo centric granulomas. Diagnosis may be difficult and involves a strong index of suspicion. There are plentiful studies are published which render the disease more frequently than expected. The strategy for imaging IGM depends on patient age, clinical manifestations, and risk factors. Patients have an excellent prognosis when they are appropriately treated. The management remains contentious, good judgment is required to ensure optimum treatment form and timing.

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“…Thickening of the skin, an irregular hypoechogenic mass with tubular extensions, smooth-edged hypoechogenic mass, hypohyperechogenic-heterogeneous mass, masses that tend to coalesce, heterogeneous parenchyma, parenchymal edema, distortion, acoustic shadowing, abscess, sinus tract formation, or lymphadenopathy may be detected. The lesions are generally soft on elastography (28). MRI is a follow-up tool in aggressive, diffuse, and irresponsive diseases.…”

Section: Idiopathic Granulomatous Mastitismentioning

confidence: 99%