Diagnostic and Physiologic Implications of the Angiotensin Infusion Test

Nicotero, James A.; Moutsos, Spero E.; Perez-Stable, Eliseo; Turrian, H; Shapiro, Alvin P.

doi:10.1056/nejm196606302742603

Cited by 15 publications

(2 citation statements)

References 8 publications

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“…Attenuated responsiveness has been found in malignant and renovascular hypertension (Kaplan and Silah, 1964;Hocken et al, 1966;Nicotero et at. * 1966), in cardiac insufficiency, nephrotic syndrome, or hepatic cirrhosis (Johnston and Jose, 1963;Laragh, 1962;Laragh et al, 1964;Kaplan and Silah, 1964), during sodium depletion (Ames et al, 1965), in pregnancy (Chesley et ao., 1965), mi Addison's disease (Kfichel et al, 1964), and in Bartter's syndrome (Bartter et al, 1962;Beilin et a!., 1967).…”

Section: Discussionmentioning

confidence: 99%

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Plasma Renin Activity and Angiotensin Pressor Dose in Hypertension: Correlation and Diagnostic Implications

Weidmann¹,

Endres²,

Siegenthaler³

1968

BMJ

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IntoductionExtensive experimental and clinical studies during recent years have shown the importance of the renin-angiotensinaldosterone system in the regulation of sodium and water balance. There is, however, still some controversy about the significance of these substances in the pathogenesis of hypertension. The fact that markedly raised secretion of renin, angiotensin, and aldosterone may be associated with normal or even reduced blood pressure has been a perpetual source of doubt in this connexion (Gross et al., 1964 ;Brown et al., 1967).The elaboration of methods of assessing these three substances has facilitated the diagnosis of certain forms of hypertension. The combination of high blood pressure, low renin, and elevated aldosterone suggests Conn's syndrome Brown et al., 1965;Weidmann et al., 1967b). Stimulation of the renin-releasing mechanisms seems to be more effective in patients with renovascular hypertension than in those with essential hypertension (Weidmann et al., 1967a) (Breckenridge, 1965 ;Fitz et al., 1965)

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Section: Discussionmentioning

confidence: 99%

“…However, Cottier et at. (1966 and Nicotero et al (1966) found it to be of limited value, and other groups (Breckenridge, 1965 ;Fitz et al, 1965) denied the utility of the technique.…”

Section: Intoductionmentioning

confidence: 99%