Diagnostic Efficacy and Safety of Endobronchial Ultrasound‐Guided Transbronchial Needle Aspiration in Intrathoracic Tuberculosis

Wu, Ye; Zhang, Ruifeng; Xu, Xiaoling; Liu, Yanru; Ying, Kejing

doi:10.7863/ultra.15.14.06017

Cited by 52 publications

(29 citation statements)

References 22 publications

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“…However, the pooled sensitivity for the diagnosis of intrathoracic TBLA was higher at 0.87. In another meta-analysis of studies involving 809 patients, the pooled diagnostic yield of EBUS-TBNA for TBLA was 80% [29]. EBUS-TBNA was also found to exhibit a diagnostic yield as high as 96.6% in cases of mediastinal TB, which presents a diagnostic challenge for clinicians [30].…”

Section: Main Textmentioning

confidence: 99%

Role of Convex Probe Endobronchial Ultrasound in the Diagnosis and Treatment of Nonmalignant Diseases

Aljohaney

2019

Pulmonary Medicine

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Here we present a comprehensive review of the literature concerning the utility of convex probe endobronchial ultrasound (CP-EBUS) in the diagnosis and treatment of nonmalignant conditions and discuss the associated complications. CP-EBUS has been conventionally used for the staging of lung cancer and sampling of mediastinal and hilar nodes. However, its application is not limited to malignant conditions, and it is gaining acceptance as a diagnostic modality of choice for nonmalignant conditions such as tuberculosis, sarcoidosis, pulmonary embolism, thyroid lesions, and cysts. Moreover, its therapeutic value allows for extended applications such as mediastinal and thyroid cyst drainage, fiducial marker placement for radiation therapy, and transbronchial needle injection. The noninvasiveness, low complication rate, high diagnostic yield, and satisfactory sensitivity and specificity values are the main attributes that lend credence to the use of CP-EBUS as a standalone primary diagnostic and therapeutic tool in pulmonary medicine in the foreseeable future.

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Section: Main Textmentioning

confidence: 99%

Role of Convex Probe Endobronchial Ultrasound in the Diagnosis and Treatment of Nonmalignant Diseases

Aljohaney

2019

Pulmonary Medicine

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“… 9 - 11 EBUS-TBNA has been shown to be an effective diagnostic tool in extrapulmonary tuberculosis, with a high sensitivity and a diagnostic yield of 80-94%, because it can reach mediastinal and hilar LNs that are commonly involved, so that the samples can be sent to cytological and microbiological analysis. 10 , 11 , 16 - 18 However, the positive culture rate for tuberculosis in this type of sample is reported to be 14-62%, which might be due to the scarcity of AFB in the LNs or lack of suitable cellular material in samples obtained from necrotic tissue. 9 , 16 , 18 , 19 In our study, EBUS-TBNA diagnosed tuberculosis in 4 cases, half of which were diagnosed by means of aspirate smears together with necrotizing granulomas or reactive LNs.…”

Section: Discussionmentioning

confidence: 77%

The role of endobronchial ultrasound-guided transbronchial needle aspiration in isolated intrathoracic lymphadenopathy in non-neoplastic patients: a common dilemma in clinical practice

et al. 2020

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“…[ 17 ] A meta-analysis showed sensitivity of EBUS-TBNA for diagnosis of intrathoracic tuberculous lymphadenopathy was 87%. [ 18 ] Another study demonstrated diagnostic value of 95.4% for EBUS-TBNA in intrathoracic tuberculous lymphadenitis (TBLA). [ 19 ] When culture and histology were combined, EBUS-TBNA demonstrated 98% accuracy for the diagnosis of mediastinal TBLA.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in solitary mediastinal, hilar lymphadenectasis, or peribronchial lesions

Chen

Jiang²,

Mao³

et al. 2016

Medicine

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Background:Patients with isolated mediastinal or hilar lymphadenopathy, or peribronchial lesions, are common presentation to clinicians. Due to the difficulty in tissue sampling, the pathological diagnosis is not so easy. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an established, highly effective, minimally invasive technique for sampling. The current study was conducted to investigate the value of EBUS-TBNA in patients of solitary mediastinal, hilar lymphadenectasis, or peribronchial lesions.Methods:Six patients with different pathological results diagnosed via EBUS-TBNA were retrospectively analyzed in this study.Results:All 6 patients of solitary mediastinal, hilar lymphadenectasis, or peribronchial lesions underwent conventional flexible bronchoscopy before EBUS-TBNA, but only EBUS-TBNA was helpful for the finally definite diagnosis. No complication was observed.Conclusion:EBUS-TBNA is a safe and highly effective diagnostic procedure for both benign and malignant diseases, especially for patients with solitary mediastinal, hilar lymphadenectasis, or peribronchial lesions.

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Diagnostic Efficacy and Safety of Endobronchial Ultrasound‐Guided Transbronchial Needle Aspiration in Intrathoracic Tuberculosis

Abstract: Endobronchial US-guided TBNA is an effective and safe diagnostic tool for intrathoracic TB, especially intrathoracic tuberculous lymphadenopathy.

Cited by 52 publications

References 22 publications

Role of Convex Probe Endobronchial Ultrasound in the Diagnosis and Treatment of Nonmalignant Diseases

Role of Convex Probe Endobronchial Ultrasound in the Diagnosis and Treatment of Nonmalignant Diseases

The role of endobronchial ultrasound-guided transbronchial needle aspiration in isolated intrathoracic lymphadenopathy in non-neoplastic patients: a common dilemma in clinical practice

Diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in solitary mediastinal, hilar lymphadenectasis, or peribronchial lesions

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